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Diterpenoids with an unusual tricyclo[10.3.0.02,9]pentadecane skeleton from Pedilanthus tithymaloides as multidrug resistance modulators
期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 138
Authors:
Zhang, Lan-Jun
;
Huang, Pei-Zhi
;
Li, Ke-Jing
;
Cao, Yue-Yang
;
Sun, Yue
;
Feng, Wei-Jiao
;
Wang, Yu-Xian
;
He, Yi-Lin
;
Mi, Le-Yuan
;
Wei, Yan-Li
...
Zhang, Lan-Jun
;
Huang, Pei-Zhi
;
Li, Ke-Jing
;
Cao, Yue-Yang
;
Sun, Yue
;
Feng, Wei-Jiao
;
Wang, Yu-Xian
;
He, Yi-Lin
;
Mi, Le-Yuan
;
Wei, Yan-Li
;
Lai, Qi-Zhong
;
Chen, Jian-Jun
;
Gao, Kun
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  |  
  
Submit date:2023/11/28
Pedilanthus tithymaloides
Jatrophanes
Pedilanins A -L
Diterpenoids
Multidrug resistance modulators
MYC Oncogene: A Druggable Target for Treating Cancers with Natural Products
期刊论文
AGING AND DISEASE, 2023
Authors:
Chan, Ka Iong
;
Zhang, Siyuan
;
Li, Guodong
;
Xu, Yida
;
Cui, Liao
;
Wang, Yitao
;
Su, Huanxing
;
Tan, Wen
;
Zhong, Zhangfeng
Favorite
  |  
  
Submit date:2023/11/28
MYC
cancer
immune response
multidrug resistance
natural product
herbal medicine
Licorice Ameliorates Cisplatin-Induced Hepatotoxicity Through Antiapoptosis, Antioxidative Stress, Anti-Inflammation, and Acceleration of Metabolism
期刊论文
Frontiers in Pharmacology, 2020, 卷号: 11
Authors:
Man, Qiong
;
Deng, Yi
;
Li, Pengjie
;
Ma, Jun
;
Yang, Zhijun
;
Yang, Xiujuan
;
Zhou, Yan
;
Yan, Xiao
Adobe PDF(6362Kb)
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  |  
  
Submit date:2020/12/17
cisplatin
detoxification
hepatotoxicity
licorice
proteomics
Global Analysis of miRNA Signature Differentially Expressed in Insulin-resistant Human Hepatocellular Carcinoma Cell Line
期刊论文
International Journal of Medical Sciences, 2020, 卷号: 17, 期号: 5, 页码: 664-677
Authors:
Li, Linjing
;
Cheng, Yan
;
Lin, Li
;
Liu, Zhuan
;
Du, Shengfang
;
Ma, Li
;
Li, Jing
;
Peng, Zhiheng
;
Yan, Jing
Adobe PDF(2356Kb)
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  |  
  
Submit date:2020/08/20
insulin resistance
HCC
miRNA Signature
AZT and emodin exhibit synergistic growth-inhibitory effects on K562/ADM cells by inducing S phase cell cycle arrest and suppressing MDR1 mRNA/p-gp protein expression
期刊论文
PHARMACEUTICAL BIOLOGY, 2013, 卷号: 51, 期号: 12, 页码: 1586-1591
Authors:
Chen, P
;
Liu, YX
;
Sun, YQ
;
Chen, C
;
Qi, YM
;
Zhang, YM(张迎梅)
;
Zhang, YM (reprint author), Lanzhou Univ, Sch Life Sci, 222 South Tianshui RD, Lanzhou 730000, Peoples R China.
Adobe PDF(728Kb)
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Submit date:2015/12/14
Cancer Cells
Myelogenous Leukemia
Synergistic Effect
Dynamics of the voluntary respiratory neural network in chronic obstructive pulmonary disease assess with cerebral functional magnetic resonance imaging
期刊论文
FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2013, 卷号: 27, 页码: 85-85
Authors:
Hess, A
;
Yu, L
;
Klein, I
;
De Mazancourt, M
;
Jebrak, G
;
Mal, H
;
Fournier, M
;
Schouman-Clayes, E
;
Courbage, M
;
Clerici, C
...
Hess, A
;
Yu, L
;
Klein, I
;
De Mazancourt, M
;
Jebrak, G
;
Mal, H
;
Fournier, M
;
Schouman-Clayes, E
;
Courbage, M
;
Clerici, C
;
Mangin, L
Adobe PDF(1269Kb)
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  |  
  
Submit date:2015/05/25
respiratory neural network-fMRI-COPD
Respiratory rhythmogenesis in healthy humans and patients with chronic obstructive pulmonary disease: a theoretical approach
期刊论文
FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2013, 卷号: 27, 页码: 85-85
Authors:
Yu, L
;
De Mazancourt, M
;
Berthault, A
;
Clerici, C
;
Courbage, M
;
Mangin, L
Adobe PDF(1269Kb)
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Submit date:2015/05/25
respiratory neural network-mathematical model-COPD
Endoplasmic reticulum stress contributes to arsenic trioxide-induced apoptosis in drug-sensitive and -resistant leukemia cells
期刊论文
LEUKEMIA RESEARCH, 2012, 卷号: 36, 期号: 12, 页码: 1526-1535
Authors:
Chen, J
;
Wei, HL(魏虎来)
;
Xie, B(谢蓓)
;
Wang, B
;
Cheng, J
;
Cheng, J
;
Wei, HL (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, 199 Donggang W Rd, Lanzhou 730000, Gansu, Peoples R China.
Adobe PDF(1187Kb)
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Submit date:2015/12/22
Arsenic trioxide
Drug resistance
Endoplasmic reticulum stress
Apoptosis
计算机辅助设计方法研究P糖蛋白多药耐药调节剂及耐药性雄激素受体抑制剂
学位论文
硕士, 兰州: 兰州大学, 2011
Authors:
吴剑华
Favorite
  |  
  
Submit date:2019/01/18
耐药性
定量构效关系
柔性对接
P糖蛋白
雄激素受体
Quantitative Structure Activity Relationship (QSAR) Approach to Multiple Drug Resistance (MDR) Modulators Based on Combined Hybrid System
期刊论文
QSAR COMB SCI, 2009, 卷号: 28, 期号: 9, 页码: 969-978
Authors:
Wu, JH
;
Li, X
;
Cheng, WD(程卫东)
;
Xie, QJ
;
Liu, YQ(刘映前)
;
Zhao, CY(赵春燕)
;
Wu, JH (reprint author), Lanzhou Univ, Sch Pharmaceut, Lanzhou 730000, Peoples R China.
Adobe PDF(355Kb)
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Submit date:2015/12/29
Drug design
P-Glycoprotein (PGP)
Quantitative structure activity relationship (QSAR)
Hybrid system, Medicinal chemistry