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兰州大学机构库

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Hemoglobin binding and antioxidant activity in spinal cord neurons: O-methylated isoflavone glycitein as a potential small molecule 期刊论文
Arabian Journal of Chemistry, 2023, 卷号: 16, 期号: 10
Authors:  Luo, Xiangli;  Wang, Zhan;  Xu, Jiancheng;  Gao, Zhao;  Song, Zhengdong;  Wang, Wenji
Favorite  |    Submit date：2023/11/28
Interaction  Hemoglobulin  Glycitein  Spectroscopy  Antioxidant  
新白叶藤碱衍生物 Z24对灰葡萄孢菌的作用机制及靶标研究 学位论文
理学博士, 兰州: 兰州大学, 2023
Authors:  赵文斌
Favorite  |    Submit date：2023/11/15
新白叶藤碱衍生物Z24  neocryptolepine derivative Z24  灰葡萄孢菌  B. cinerea  分子靶标  molecular target  硫胺噻唑合酶  thiaminothiazole synthase  可变剪接  variable splicing  硫胺素代谢  thiamine metabolism  虚拟筛选  virtual screening  
Synthesis and evaluation of Piperine analogs as thioredoxin reductase inhibitors to cause oxidative stress-induced cancer cell apoptosis 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 138
Authors:  Zhong, Miao;  Chen, Lingzhen;  Tao, Yue;  Zhao, Jintao;  Chang, Bingbing;  Zhang, Fang;  Tu, Jingwen;  Cai, Wenqing;  Zhang, Baoxin
Favorite  |    Submit date：2023/11/28
Piperine analogs  Thioredoxin reductase inhibitors  Reactive oxygen species  Oxidative stress  Apoptosis  
Anti-inflammatory efficacy and relevant SAR investigations of novel chiral pyrazolo isoquinoline derivatives: Design, synthesis, in-vitro, in-vivo, and computational studies targeting iNOS 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256
Authors:  Akhtar, Maryam;  Niu, Jiabin;  Zhu, Yujie;  Luo, Zhaoyi;  Tian, Ting;  Dong, Yuanliang;  Wang, Yuan;  Fareed, Muhammad Subaan;  Lin, Li
Favorite  |    Submit date：2023/07/18
Anti-inflammatory  Pyrazolo isoquinoline  Nitric oxide inhibition  Inducible nitric oxide synthase  Celecoxib  
Modulation of feed digestibility, nitrogen metabolism, energy utilisation and serum biochemical indices by dietary Ligularia virgaurea supplementation in Tibetan sheep 期刊论文
Animal, 2023, 卷号: 17, 期号: 8
Authors:  Cui, Xiongxiong;  Wang, Zhaofeng;  Yan, Tianhai;  Chang, Shenghua;  Hou, Fujiang
Favorite  |    Submit date：2023/11/28
Alpine meadow pasture  Functional native herbage  Grazing  Qinghai-Tibetan Plateau  Sustainability  
Mechanism of ligusticum cycloprolactam against neuroinflammation based on network pharmacology and experimental verification 期刊论文
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2023, 卷号: 50, 期号: 8, 页码: 647-663
Authors:  Gao, Juan;  Su, Gang;  Chen, Wei;  Wu, Qionghui;  Liu, Junxi;  Liu, Jifei;  Chai, Miao;  Dong, Ying;  Wang, He;  Chen, Lixia...Gao, Juan;  Su, Gang;  Chen, Wei;  Wu, Qionghui;  Liu, Junxi;  Liu, Jifei;  Chai, Miao;  Dong, Ying;  Wang, He;  Chen, Lixia;  Zhang, Zhenchang;  Wang, Manxia
Favorite  |    Submit date：2023/07/18
BV2 microglia cells  HT22 cells  ligusticum cycloprolactam  network pharmacology  neuroinflammation  NF-kappa B  
Discovery and Design of Novel Cyclic Peptides as Specific Inhibitors Targeting CCN2 and Disrupting CCN2/EGFR Interaction for Kidney Fibrosis Treatment 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2023
Authors:  Dong, Jiale;  Xiao, Jing;  Li, Jianyi;  Yu, Huan;  Zhao, Qian;  Tang, Qinglin;  Chen, Hui;  Liu, Han;  Wu, Kejue;  Lei, Jinping...Dong, Jiale;  Xiao, Jing;  Li, Jianyi;  Yu, Huan;  Zhao, Qian;  Tang, Qinglin;  Chen, Hui;  Liu, Han;  Wu, Kejue;  Lei, Jinping;  Wang, Rui;  Jiang, Xianxing
Favorite  |    Submit date：2023/07/18
光诱导铜催化的手性非天然芳香族氨基酸的制备 学位论文
医学硕士, 兰州: 兰州大学, 2023
Authors:  王红鹰
Favorite  |    Submit date：2023/11/15
光化学合成  Photochemical synthesis  铜催化反应  copper catalyzed reactions  手性分子  chiral molecules  非天然芳香族氨基酸  unnatural aromatic amino acids  立体选择性苄基化  stereoselective benzylation  
体外培育牛黄工程菌的优化研究及牛黄在牙周炎治疗中的药理预测 学位论文
医学硕士, 兰州: 兰州大学, 2023
Authors:  卢纪元
Favorite  |    Submit date：2023/11/15
体外培育  In vitro cultivation  牛黄  bezoar  工程菌  engineered bacteria  牙周炎  periodontitis.  
靶向CDK6抑制剂及降解剂的虚拟筛选与化学合成研究 学位论文
药学硕士, 兰州: 兰州大学, 2023
Authors:  张豪
Favorite  |    Submit date：2023/11/15
CDK6  CDK6  抑制剂  Inhibitor  PROTAC  PROTAC  组合化学  Combinatorial Chemistry  数据库  Database  虚拟筛选  Virtual screening