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兰州大学机构库

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Sesamol as a potential small molecule in inhibiting the induction of neurotoxic amyloids fibrils involved in the pathophysiology of alzheimer's disease 期刊论文
Arabian Journal of Chemistry, 2023, 卷号: 16, 期号: 9
Authors:  Cai, Hong-Bin;  Li, Ming -Ming;  Ting, Tian;  Yao, Min;  Pan, Ya-Wen;  Sui, Rupo
Favorite  |    Submit date：2023/11/28
a-Synuclein  Sesamol  Amyloid  Inhibition  Neurotoxicity  
外界因素与小分子对α-突触核蛋白错误折叠和聚集影响的分子模拟研究 学位论文
药学硕士, 兰州: 兰州大学, 2023
Authors:  赵楠楠
Favorite  |    Submit date：2023/11/15
α-突触核蛋白  α-synuclein  错误折叠和聚集  misfolding and aggregation  多态性  polymorphism  交叉播种  cross-seeding  多酚类抑制剂  polyphenol inhibitors  分子动力学模拟  molecular dynamics simulation  
Inhibitory mechanism of n-MTAB AuNPs for alpha-synuclein aggregation 期刊论文
JOURNAL OF MOLECULAR MODELING, 2023, 卷号: 29, 期号: 4
Authors:  Liu, Rui Rui;  Zhai, Hong Lin;  Zhu, Min;  Shao, Hai Ping;  Wang, Tian Hua
Favorite  |    Submit date：2023/05/25
Alpha-synuclein (alpha-syn)  n-MTAB AuNPs  Interaction mechanism  Directional binding  Molecular dynamics (MD)  
The alpha-Synuclein Monomer May Have Different Misfolding Mechanisms in the Induction of alpha-Synuclein Fibrils with Different Polymorphs 期刊论文
BIOMOLECULES, 2023, 卷号: 13, 期号: 4
Authors:  Zhao, Nannan;  Zhang, Qianqian;  Yu, Fansen;  Yao, Xiaojun;  Liu, Huanxiang
Favorite  |    Submit date：2023/07/18
alpha-synuclein fibrils  template-induced misfolding  steered MD simulation  DCCM  secondary structure analysis  residue interaction network  
Rose essential oil diminishes dopaminergic neuron degenerations and reduces alpha-synuclein aggregation in Caenorhabditis elegans models of Parkinson's disease 期刊论文
PHYTOTHERAPY RESEARCH, 2023, 卷号: 37, 期号: 7, 页码: 2877-2893
Authors:  Muhammad, Fahim;  Liu, Yan;  Wang, Ningbo;  Zhao, Longhe;  Zhou, Yangtao;  Yang, Hui;  Li, Hongyu
Favorite  |    Submit date：2023/04/12
6-hydroxydopamine  Caenorhabditis elegans  Parkinson's disease  reactive oxygen species  rose essential oil  alpha-Synuclein  
Neuroprotective effects of cannabidiol on dopaminergic neurodegeneration and ?-synuclein accumulation in C. elegans models of Parkinson?s disease 期刊论文
NEUROTOXICOLOGY, 2022, 卷号: 93, 页码: 128-139
Authors:  Muhammad, Fahim;  Liu, Yan;  Wang, Ningbo;  Zhao, Longhe;  Zhou, Yangtao;  Yang, Hui;  Li, Hongyu
Favorite  |    Submit date：2023/01/03
Parkinson disease  Caenorhabditis elegans  Cannabidiol  Proteasome  ?-Synuclein  Reactive oxygen species  
Rotenone aggravates PD-like pathology in A53T mutant human a-synuclein transgenic mice in an age-dependent manner 期刊论文
Frontiers in Aging Neuroscience, 2022, 卷号: 14
Authors:  Chen, An-Di;  Cao, Jia-Xin;  Chen, Hai-Chao;  Du, Hong-Li;  Xi, Xiao-Xia;  Sun, Jing;  Yin, Jie;  Jing, Yu-Hong;  Gao, Li-Ping
Favorite  |    Submit date：2022/11/09
Parkinson's disease  human a-syn(+-) (A53T)  rotenone  aging  brain-gut axis  
Parkinson's Disease Derived Exosomes Aggravate Neuropathology in SNCAA53T Mice 期刊论文
ANNALS OF NEUROLOGY, 2022, 卷号: 92, 期号: 2, 页码: 230-245
Authors:  Huang, Yang;  Liu, Zongran;  Li, Na;  Tian, Chen;  Yang, Han;  Huo, Yanfei;  Li, Yang;  Zhang, Jing;  Yu, Zhenwei
Favorite  |    Submit date：2022/07/25
Antioxidative role of Traditional Chinese Medicine in Parkinson's disease 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 285
Authors:  Muhammad, Fahim;  Liu, Yan;  Zhou, Yongtao;  Yang, Hui;  Li, Hongyu
Favorite  |    Submit date：2022/07/01

Parkinson & rsquo  s disease, Reactive oxygen species

  Traditional Chinese Medicine  Alpha synuclein  Dopaminergic neuron  
Anti-alpha-synuclein Toxicity and Anti-neurodegenerative Role of Chrysin in Transgenic Caenorhabditis elegans Models of Parkinson's Disease 期刊论文
ACS Chemical Neuroscience, 2022, 卷号: 13, 期号: 4, 页码: 442-453
Authors:  Muhammad, Fahim;  Liu, Yan;  Wang, Ningbo;  Zhao, Longhe;  Zhou, Yongtao;  Yang, Hui;  Li, Hongyu
Favorite  |    Submit date：2022/07/01
Parkinson's disease  chrysin  6-hydroxydopamine  alpha-synuclein  Caenorhabditis elegans  proteasome  oxidative stress