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Formulation of DOX-dimer with bi-functionalized chitooligosaccharide for tumor-specific self-boosted drug release and synergistic chemo/chemodynamic therapy
期刊论文
CARBOHYDRATE POLYMERS, 2023, 卷号: 320
Authors:
Xie, Pengwei
;
Liu, P(刘鹏)
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  |  
  
Submit date:2023/09/04
Controlled drug delivery
Drug products
Oxidation
Targeted drug delivery
Chemodynamics
Chitooligosaccharides
Doxorubicin
Drug release
Functionalized
Functionalized chitooligosaccharide
Ph/reactive oxygen species dual-triggered
Reactive oxygen species
Reactive oxygen species-activated doxorubicin-based dimer
Self-boosted drug release
Synergistic chemo/chemodynamic therapy
Integrated bioinformatics analysis and network pharmacology to explore the potential mechanism of Patrinia heterophylla Bunge against acute promyelocytic leukemia
期刊论文
MEDICINE, 2023, 卷号: 102, 期号: 40
Authors:
Feng, Liya
;
Zhu, Sha
;
Ma, Jian
;
Hong, Yali
;
Wan, Meixia
;
Qiu, Qian
;
Li, Hongjing
;
Li, Juan
Favorite
  |  
  
Submit date:2023/11/28
acute promyelocytic leukemia
bioinformatics analysis
molecular docking
network pharmacology
Patrinia heterophylla Bunge
Heparanase inhibition leads to improvement in patients with acute gastrointestinal injuries induced by sepsis
期刊论文
WORLD JOURNAL OF GASTROENTEROLOGY, 2023, 卷号: 29, 期号: 35
Authors:
Chen, Ting-Ting
;
Lv, Jia-Jun
;
Chen, Ling
;
Li, Min
;
Liu, Li-Ping
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  |  
  
Submit date:2023/11/28
Sepsis
Acute gastrointestinal injury
Heparanase
Autophagy
光敏钌配合物 MOFs 的合成、 结构调控及其光催化反应研 究
学位论文
理学博士, 兰州: 兰州大学, 2023
Authors:
白东杰
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  |  
  
Submit date:2023/11/15
光敏 MOFs
photosensitizing MOFs
光催化
photocatalysis
还原 CO2
reduction of CO2
C-N 偶联反应
C-N coupling reaction
C-C 偶联反应
C-C coupling reaction
Direct bromoalkoxylation of enones under acid-free conditions
期刊论文
TETRAHEDRON LETTERS, 2023, 卷号: 126
Authors:
Fang, Bowen
;
Zhai, Lele
;
Li, Zhongqin
;
Li, Huilin
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  |  
  
Submit date:2023/11/28
Enone
Difunctionalization
Bromoalkoxylation
Acid-free
Green synthesis
氟聚赖氨酸跨黏膜递送CRISPR/Cas9系统靶向DAD1基因用于膀胱癌灌注治疗的研究
学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:
汤栋栋
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  |  
  
Submit date:2023/11/15
氟聚赖氨酸
fluorinated polylysine
CRISPR-Cas9
CRISPR-Cas9
DAD1
DAD1
膀胱癌
bladder cancer
灌注治疗
intravesical therapy
超声联合多功能纳米复合物在NSCLC分子靶向治疗的应用研究
学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:
吕文豪
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  |  
  
Submit date:2023/11/15
NSCLC
NSCLC
TAMs
TAMs
光热治疗
photothermal therapy
金基纳米复合物
gold-based nanocomplexes
声动力治疗
Sonodynamic therapy
EGFR-TKI耐药
EGFR-TKI resistance
超声增强成像
Contrast-enhanced ultrasound imaging
刺激响应性嘌呤霉素前药和嘌呤霉素衍生物 的合成及生物应用
学位论文
理学博士, 兰州: 兰州大学, 2023
Authors:
chang bingbing
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  |  
  
Submit date:2023/11/15
嘌呤霉素
Puromycin
刺激响应性前药
Stimuli-responsive prodrugs
内源性刺激
Endogenous stimuli
外源性刺激
Exogenous stimuli
二硫/二硒结构
Disulfide/diselenide scaffolds
硫氧还蛋白还原酶
Thioredoxin reductase
谷胱甘肽
Glutathione
二硫苏糖醇
Dithiothreitol
1,2,3-三氮唑
1,2,3-Triazoles
自适应纳米诊疗系统用于预防与治疗植入物感染的研究
学位论文
医学硕士, 兰州: 兰州大学, 2023
Authors:
易俊丹
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  |  
  
Submit date:2023/11/15
植入物感染
Implant-related infections
自适应纳米诊疗系统
Self-adaptive theranostics nanosystem
相变材料
Phase change materials
细菌生物膜
Bacterial biofilm
免疫记忆
Immune memory
基于天然产物的抗脓毒症器官损伤药物的设计、合成及活性研究
学位论文
医学硕士, 兰州: 兰州大学, 2023
Authors:
王宗元
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  |  
  
Submit date:2023/11/15
红景天苷,甘草次酸,脓毒症,心肌损伤,急性肾损伤
salidroside
glycyrrhetinic acid
sepsis
myocardial injury
acute kidney injury