兰州大学机构库

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Curcumin Affects Gastric Cancer Cell Migration, Invasion and Cytoskeletal Remodeling Through Gli1-beta-Catenin 期刊论文
Cancer Management and Research, 2020, 卷号: 12, 页码: 3795-3806
Authors:  Zhang, Xiao;  Zhang, Chenli;  Ren, Zhiheng;  Zhang, Fangfang;  Xu, Jinyu;  Zhang, Xu;  Zheng, Haixue
Adobe PDF(6213Kb)  |  Favorite  |    Submit date:2020/07/13
curcumin  Gli1  beta-catenin  migration  invasion  cytoskeleton  
Discovery of Novel Inhibitor for WNT/beta-Catenin Pathway by Tankyrase 1/2 Structure-Based Virtual Screening 期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 7
Authors:  Li, Bo;  Liang, Jinxia;  Lu, Feng;  Zeng, Guandi;  Zhang, Jindao;  Ma, Yinxing;  Liu, Peng;  Wang, Q(王勤);  Zhou, Qian;  Chen, Liang...Li, Bo;  Liang, Jinxia;  Lu, Feng;  Zeng, Guandi;  Zhang, Jindao;  Ma, Yinxing;  Liu, Peng;  Wang, Q(王勤);  Zhou, Qian;  Chen, Liang
Adobe PDF(4367Kb)  |  Favorite  |    Submit date:2020/07/13
tankyrase 1  2 inhibitors  WNT  beta-catenin signaling pathway  virtual screening  dock  antitumor  
A novel UBE2T inhibitor suppresses Wnt/beta-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination 期刊论文
ONCOGENE, 2021, 卷号: 40, 期号: 5, 页码: 1027-1042
Authors:  Yu, Zeyuan;  Jiang, Xiangyan;  Qin, Long;  Deng, Haixiao;  Wang, Jianli;  Ren, Wen;  Li, Hongbin;  Zhao, Lei;  Liu, HX(刘焕香);  Yan, Hong...Yu, Zeyuan;  Jiang, Xiangyan;  Qin, Long;  Deng, Haixiao;  Wang, Jianli;  Ren, Wen;  Li, Hongbin;  Zhao, Lei;  Liu, HX(刘焕香);  Yan, Hong;  Shi, Wengui;  Wang, Qi;  Luo, Changjiang;  Long, Bo;  Zhou, Huinian;  Sun, Hui;  Jiao, Zuoyi
Adobe PDF(7514Kb)  |  Favorite  |    Submit date:2021/04/16
基于肝癌细胞研究PA-MSHA抑制PD-L1及sPD-L1的机制 学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:  魏航之
Favorite  |    Submit date:2023/11/15
肝细胞癌  HCC  PA-MSHA  PA-MSHA  β-catenin  β-catenin  甘露糖基  mannosyl  PD-L1  PD-L1  sPD-L1  sPD-L1  
Chronic CagA-positive Helicobacter pylori infection with MNNG stimulation synergistically induces mesenchymal and cancer stem cell-like properties in gastric mucosal epithelial cells 期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 卷号: 120, 期号: 10, 页码: 17635-17649
Authors:  Lin, L(林利);  Wei, HL(魏虎来);  Yi, J(易娟);  Xie, B(谢蓓);  Chen, J(陈静);  Zhou, Cunmin;  Wang, L(王莉);  Yang, Yue
Adobe PDF(2726Kb)  |  Favorite  |    Submit date:2020/08/06
C57BL  6 mice  CagA-positive Helicobacter pylori  cancer stem cell-like properties  epithelial-mesenchymal transition (EMT)  Immortalized human gastric epithelial cells (GES-1)  N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)  Wnt  beta-catenin signaling pathway  
新型UBE2T抑制剂通过阻止RACK1泛素化抑制Wnt/β-catenin信号通路激活及胃癌生长 学位论文
医学博士, 兰州: 兰州大学, 2021
Authors:  俞泽元
Favorite  |    Submit date:2021/12/06
胃癌  泛素结合酶E2T  抑制剂  
GSK3β在稽留流产中的作用和机制研究 学位论文
医学硕士, 兰州: 兰州大学, 2021
Authors:  郑蓉
Favorite  |    Submit date:2023/11/15
稽留流产  missed abortion (MA)  GSK3β  GSK3β  PI3K/AKT信号通路  PI3K/AKT pathway  Wnt/β-catenin信号通路  Wnt/β-catenin pathway  MCL-1  MCL-1  
Developing a Versatile Shotgun Cloning Strategy for Single-Vector-Based Multiplex Expression of Short Interfering RNAs (siRNAs) in Mammalian Cells 期刊论文
ACS Synthetic Biology, 2019, 卷号: 8, 期号: 9, 页码: 2092-2105
Authors:  Wang, Xi;  Yuan, Chengfu;  Huang, Bo;  Fan, Jiaming;  Feng, Yixiao;  Li, Alexander J.;  Zhang, Bo;  Lei, Yan;  Ye, Zhenyu;  Zhao, Ling...Wang, Xi;  Yuan, Chengfu;  Huang, Bo;  Fan, Jiaming;  Feng, Yixiao;  Li, Alexander J.;  Zhang, Bo;  Lei, Yan;  Ye, Zhenyu;  Zhao, Ling;  Cao, Daigui;  Yang, Lijuan;  Wu, Di;  Chen, Xian;  Liu, Bin;  Wagstaff, William;  He, Fang;  Wu, Xiaoxing;  Luo, Huaxiu;  Zhang, Jing;  Zhang, Meng;  Haydon, Rex C.;  Luu, Hue H.;  Lee, Michael J.;  Wolf, Jennifer Moriatis;  Huang, Ailong;  He, Tong-Chuan;  Zeng, Zongyue
Adobe PDF(2810Kb)  |  Favorite  |    Submit date:2020/08/04
RNA interference (RNAi)  short interfering double-stranded RNA (siRNA)  Wnt/beta-catenin signaling  BMP9/Smad4 signaling  mesenchymal stem cells (MSCs)  osteogenic differentiation  multiplex expression  shotgun cloning  
狼疮性肾炎患者治疗无反应的临床风险因素及Wnt/β-Catenin信号通路的作用 学位论文
硕士, 兰州: 兰州大学, 2017
Authors:  张育榕
Favorite  |    Submit date:2019/01/17
系统性红斑狼疮  狼疮肾炎  诱导治疗  风险因素  Wnt/β-Catenin  狼疮性肾炎  病理机制  免疫微环境  
COX2对骨肉瘤MG63细胞转移侵袭迁移的调控及其分子机制探索 学位论文
博士, 兰州: 兰州大学, 2018
Authors:  张学良
Favorite  |    Submit date:2020/01/15
Cox-2  上皮间质转化  骨肉瘤  PI3K/AKT/NF-κB信号通路