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Occurrence and fate of antibiotic-resistance genes and their potential hosts in high-moisture alfalfa silage treated with or without formic acid bactericide
期刊论文
JOURNAL OF ENVIRONMENTAL MANAGEMENT, 2023, 卷号: 347
Authors:
Zhang, Xia
;
Usman, Samaila
;
Bature, Ibrahim
;
Xu, Dongmei
;
Guo, Xusheng
Favorite
  |  
  
Submit date:2023/11/28
Antibiotic resistance genes
High -moisture alfalfa silage
Bactericide
Clinical ARGs
Mobile genetic elements
Diterpenoids with an unusual tricyclo[10.3.0.02,9]pentadecane skeleton from Pedilanthus tithymaloides as multidrug resistance modulators
期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 138
Authors:
Zhang, Lan-Jun
;
Huang, Pei-Zhi
;
Li, Ke-Jing
;
Cao, Yue-Yang
;
Sun, Yue
;
Feng, Wei-Jiao
;
Wang, Yu-Xian
;
He, Yi-Lin
;
Mi, Le-Yuan
;
Wei, Yan-Li
...
Zhang, Lan-Jun
;
Huang, Pei-Zhi
;
Li, Ke-Jing
;
Cao, Yue-Yang
;
Sun, Yue
;
Feng, Wei-Jiao
;
Wang, Yu-Xian
;
He, Yi-Lin
;
Mi, Le-Yuan
;
Wei, Yan-Li
;
Lai, Qi-Zhong
;
Chen, Jian-Jun
;
Gao, Kun
Favorite
  |  
  
Submit date:2023/11/28
Pedilanthus tithymaloides
Jatrophanes
Pedilanins A -L
Diterpenoids
Multidrug resistance modulators
两种大戟科植物中二萜的发现及其生物活性研究
学位论文
理学博士, 兰州: 兰州大学, 2023
Authors:
张兰军
Favorite
  |  
  
Submit date:2023/11/15
红雀珊瑚
Pedilanthus tithymaloides
绿玉树
Euphorbia tirucalli
假白榄烷型二萜
Targeted discovery
定向发现
Jatrophanes diterpenoids
跨环环化反应
Cyclization
多药耐药逆转活性
Multidrug resistance reversal activit
P 糖蛋白
Pgp
Structure-Activity Relationship Study of Antimicrobial Peptide PE2 Delivered Novel Linear Derivatives with Potential of Eradicating Biofilms and Low Incidence of Drug Resistance
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 13, 页码: 8526-8544
Authors:
Zhang, Jingying
;
Ouyang, Xu
;
Zhang, Fangyan
;
Li, Beibei
;
Chang, Linlin
;
Yang, Ping
;
Mao, Wenbo
;
Gou, Sanhu
;
Zhang, Yun
;
Liu, Hui
...
Zhang, Jingying
;
Ouyang, Xu
;
Zhang, Fangyan
;
Li, Beibei
;
Chang, Linlin
;
Yang, Ping
;
Mao, Wenbo
;
Gou, Sanhu
;
Zhang, Yun
;
Liu, Hui
;
Yao, Jia
;
Ni, Jingman
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  |  
  
Submit date:2023/11/28
MYC Oncogene: A Druggable Target for Treating Cancers with Natural Products
期刊论文
AGING AND DISEASE, 2023
Authors:
Chan, Ka Iong
;
Zhang, Siyuan
;
Li, Guodong
;
Xu, Yida
;
Cui, Liao
;
Wang, Yitao
;
Su, Huanxing
;
Tan, Wen
;
Zhong, Zhangfeng
Favorite
  |  
  
Submit date:2023/11/28
MYC
cancer
immune response
multidrug resistance
natural product
herbal medicine
基于CRISPR/Cas9技术构建有机阴离子转运体1/3双敲除大鼠模型及其基本特征评价
学位论文
药学硕士, 兰州: 兰州大学, 2023
Authors:
勾雪艳
Favorite
  |  
  
Submit date:2023/11/15
基因敲除
gene knockout
CRISPR/Cas9
CRISPR/Cas9
有机阴离子转运体1
OAT1
有机阴离子转运体3
OAT3
药动学
pharmacokinetics
创伤性颅脑损伤致肾功能亢进的临床及机制研究
学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:
党子龙
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  |  
  
Submit date:2023/11/15
创伤性颅脑损伤
Traumatic Brain Injury, Augmented Renal Clearance
肾功能亢进
Transporters
转运体
Brain-kidney axis
脑-肾轴
5-methoxyindole-3-acetic acid (5M)
5-甲氧基吲哚-3-乙酸(5M)
92例Stevens-Johnson综合征和中毒性表皮坏死松解症患者合并感染及其相关因素分析
学位论文
医学硕士, 兰州: 兰州大学, 2023
Authors:
张静
Favorite
  |  
  
Submit date:2023/11/15
Stevens⁃Johnson综合征
Stevens⁃Johnson syndrome
中毒性表皮坏死松解症
toxic epidermal necrolysis,
感染
infection
病原菌
pathogenic bacteria
耐药
drug resistance
新型半导体硒化铜铁纳米材料的制备 及抗菌性能与机制研究
学位论文
医学硕士, 兰州: 兰州大学, 2023
Authors:
Wang Meng
Favorite
  |  
  
Submit date:2023/11/15
硒化铜铁
Copper iron selenide
纳米抗菌材料
Anti-microbial nanomaterial
内容物的泄露
Leakage of intracellular components
活性氧的产生
Reactive oxygen species generation
纳米刀片锋利的边缘效应
Sharp edges effect of nano- knives
生物相容性
Biocompatibility
天然产物Crotontomentosin D和Sinopyrine B的全合成以及抗肿瘤药物高通量筛选平台的建立及应用
学位论文
医学硕士, 兰州: 兰州大学, 2023
Authors:
李晶
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  |  
  
Submit date:2023/11/15
Crotontomentosin D
Crotontomentosin D
sinopyrine B
sinopyrine B
全合成
total synthesis
高通量筛选
high-throughput screening
胰腺癌
pancreatic cancer
KRAS G12D
KRAS G12D