兰州大学机构库

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Tryptic Stability and Antimicrobial Activity of the Derivatives of Polybia-CP with Fine-Tuning Modification in the Side Chain of Lysine 期刊论文
International Journal of Peptide Research and Therapeutics, 2020, 卷号: 27, 期号: 2, 页码: 851-862
Authors:  Jia, Fengjing;  Liang, Xiaolei;  Wang, Jiayi;  Zhang, Lishi;  Zhou, Jingjing;  He, Yuhang;  Zhang, Fangfang;  Yan, Wenjin;  Wang, Kairong
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Cationic antimicrobial peptide  Polybia-CP  Tryptic stability  Fine-tuning of side chain  
Membrane-Active Action Mode of Polybia-CP, a Novel Antimicrobial Peptide Isolated from the Venom of Polybia paulista 期刊论文
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2012, 卷号: 56, 期号: 6, 页码: 3318-3323
Authors:  Wang, KR;  Yan, JX;  Chen, R;  Dang, W;  Zhang, BZ(张邦治);  Zhang, W;  Song, JJ;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Sch Life Sci,Inst Biochem & Mol Biol, Lanzhou 730000, Peoples R China.
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Novel cytotoxity exhibition mode of polybia-CP, a novel antimicrobial peptide from the venom of the social wasp Polybia paulista 期刊论文
TOXICOLOGY, 2011, 卷号: 288, 期号: 1-3, 页码: 27-33
Authors:  Wang, KR;  Yan, JX;  Liu, X;  Zhang, JD;  Chen, R;  Zhang, BZ(张邦治);  Dang, W;  Zhang, W;  Kai, M;  Song, JJ...Wang, KR;  Yan, JX;  Liu, X;  Zhang, JD;  Chen, R;  Zhang, BZ(张邦治);  Dang, W;  Zhang, W;  Kai, M;  Song, JJ;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Inst Biochem & Mol Biol, Key Lab Preclin Study New Drugs Gansu Prov, 199 Western Donggang Rd, Lanzhou 730000, Peoples R China.
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Antimicrobial peptide  Polybia-CP  Molecular dynamics simulations  Membrane perturbation  "Carpet" model  
Membrane active antimicrobial activity and molecular dynamics study of a novel cationic antimicrobial peptide polybia-MPI, from the venom of Polybia paulista 期刊论文
PEPTIDES, 2013, 卷号: 39, 页码: 80-88
Authors:  Wang, KR;  Yan, JX;  Dang, W;  Liu, X;  Chen, R;  Zhang, JD;  Zhang, BZ(张邦治);  Zhang, W;  Kai, M;  Yan, WJ...Wang, KR;  Yan, JX;  Dang, W;  Liu, X;  Chen, R;  Zhang, JD;  Zhang, BZ(张邦治);  Zhang, W;  Kai, M;  Yan, WJ;  Yang, ZB;  Xie, JQ;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Life Sci, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci,Inst Biochem & Mol Biol, 222 Tian Shui South Rd, Lanzhou 730000, Peoples R China.
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Resistant bacteria  Polybia-MPI  Membrane perturbation  Molecular dynamics study  
Dual antifungal properties of cationic antimicrobial peptides polybia-MPI: Membrane integrity disruption and inhibition of biofilm formation 期刊论文
PEPTIDES, 2014, 卷号: 56, 页码: 22-29
Authors:  Wang, KR;  Yan, JX;  Dang, W;  Xie, JQ;  Yan, B;  Yan, WJ;  Sun, MY;  Zhang, BZ(张邦治);  Ma, MX;  Zhao, YY...Wang, KR;  Yan, JX;  Dang, W;  Xie, JQ;  Yan, B;  Yan, WJ;  Sun, MY;  Zhang, BZ(张邦治);  Ma, MX;  Zhao, YY;  Jia, FJ;  Zhu, RR;  Chen, W;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 222 Tian Shui South Rd, Lanzhou 730000, Peoples R China.
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Antifungal activity  Antimicrobial peptide  Polybia-MPI Biofilm formation  
D型氨基酸替换和赖氨酸侧链微修饰对抗菌肽polybia-CP生物活性及稳定性的影响研究 学位论文
硕士, 兰州: 兰州大学, 2018
Authors:  汪嘉懿
Favorite  |    Submit date:2019/01/17
抗菌肽polybia-CP  D型氨基酸替换  赖氨酸侧链微修饰  抗菌活性  稳定性  
线粒体靶向抗菌肽Polybia-CP类似物的抗肿瘤机制研究 学位论文
医学硕士, 兰州: 兰州大学, 2023
Authors:  马玲
Favorite  |    Submit date:2023/11/15
抗菌肽  Antimicrobial peptides  黑色素瘤  melanoma  抗肿瘤机制  antitumor mechanism  线粒体损伤  mitochondrial damage  免疫原性细胞死亡  immunogenic cell death  
抗菌肽Polybia-CP的结构优化及抗肿瘤研究 学位论文
理学硕士, 兰州: 兰州大学, 2021
Authors:  贾博
Favorite  |    Submit date:2021/12/06
抗菌肽  构效关系研究  抗黑色素瘤活性  线粒体靶向分子  D型氨基酸  
Membrane Perturbation Action Mode and Structure-Activity Relationships of Protonectin, a Novel Antimicrobial Peptide from the Venom of the Neotropical Social Wasp Agelaia pallipes pallipes 期刊论文
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2013, 卷号: 57, 期号: 10, 页码: 4632-4639
Authors:  Wang, KR;  Dang, W;  Yan, JX;  Chen, R;  Liu, X;  Yan, WJ;  Zhang, BZ(张邦治);  Xie, JQ;  Zhang, JD;  Wang, R(王锐)...Wang, KR;  Dang, W;  Yan, JX;  Chen, R;  Liu, X;  Yan, WJ;  Zhang, BZ(张邦治);  Xie, JQ;  Zhang, JD;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.
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Antifungal effect and action mechanism of antimicrobial peptide polybia-CP 期刊论文
JOURNAL OF PEPTIDE SCIENCE, 2016, 卷号: 22, 期号: 1, 页码: 28-35
Authors:  Wang, KR;  Jia, FJ;  Dang, W;  Zhao, YY;  Zhu, RR;  Sun, MY;  Qiu, S;  An, XP;  Ma, ZL;  Zhu, YY...Wang, KR;  Jia, FJ;  Dang, W;  Zhao, YY;  Zhu, RR;  Sun, MY;  Qiu, S;  An, XP;  Ma, ZL;  Zhu, YY;  Yan, JX;  Kong, ZQ;  Yan, WJ;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 222 Tian Shui South Rd, Lanzhou 730000, Peoples R China.
Favorite  |    Submit date:2017/01/13
antimicrobial peptide  polybia-CP  candidiasis  antifungal  ROS production