兰州大学机构库

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A new approach for rapidly reshaping single-chain antibody in vitro by combining DNA shuffling with ribosome display 期刊论文
JOURNAL OF BIOCHEMISTRY, 2004, 卷号: 136, 期号: 1, 页码: 19-28
Authors:  Wang, XB;  Zhou, B;  Yin, CC;  Lin, Q;  Huang, HL;  Huang, HL (reprint author), Chinese Acad Sci, Inst Genet & Dev Biol, Beijing 100101, Peoples R China.
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antibody reshaping  DNA shuffling  ribosome display  single-chain antibody  
靶向c-MET和MSLN的第四代串联型CAR-T细胞的构建及其在胰腺癌中的研究 学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:  缪乐乐
Favorite  |    Submit date:2023/11/15
c-MET  c-MET  MSLN  MSLN  胰腺癌  PAAD  scFv  scFv  CAR-T细胞  CAR-T cells  
共表达IL-7/IL-21靶向c-Met的CAR-T细胞在治疗胃癌的临床前研究 学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:  张正潮
Favorite  |    Submit date:2023/11/15
胃癌  Gastric cancer  c-Met  c-Met  组织芯片  Tissue chip  靶向治疗  Targeted therapy  单克隆抗体  Monoclonal antibody  微流控技术  Microfluidic technology  scFv  scFv  CAR-T  CAR-T  IL-7  IL-7  IL-21  IL-21  免疫治疗  Immunotherapy  PDX模型  PDX model  
A new recombinant single chain trispecific antibody recruits T lymphocytes to kill CEA (carcinoma embryonic antigen) positive tumor cells in vitro efficiently 期刊论文
JOURNAL OF BIOCHEMISTRY, 2004, 卷号: 135, 期号: 4, 页码: 555-565
Authors:  Wang, XB;  Zhao, BF;  Zhao, Q;  Piao, JH;  Liu, J;  Lin, Q;  Huang, HL;  Huang, HL (reprint author), Chinese Acad Sci, Inst Genet & Dev Biol, Grp 102, Beijing 100101, Peoples R China.
Adobe PDF(592Kb)  |  Favorite  |    Submit date:2015/12/11
CD3  CD28  CEA  single chain trispecific antibody  
ZNF165 单克隆抗体的制备及功能验证 学位论文
医学硕士, 兰州: 兰州大学, 2023
Authors:  吴文章
Favorite  |    Submit date:2023/11/15
ZNF165  ZNF165  消化系肿瘤  gastrointestinal tumor  诊断及治疗  diagnosis and treatment  单克隆抗体  monoclonal antibody  MBAT  MBAT  
抗白念珠菌天然单链抗体库的构建、筛选及初步鉴定 学位论文
硕士, 兰州: 兰州大学, 2009
Authors:  路艳
Favorite  |    Submit date:2019/01/17
白念珠菌  天然抗体库  ScFv  噬菌体展示  重组基因  筛选  
广谱有机磷农药单克隆抗体、单链抗体的制备及免疫检测技术研究 学位论文
硕士, 兰州: 兰州大学, 2018
Authors:  张晓帅
Favorite  |    Submit date:2019/01/18
有机磷农药  载体蛋白  人工抗原  单克隆抗体  单链抗体  
Obstacles and Coping Strategies of CAR-T Cell Immunotherapy in Solid Tumors 期刊论文
Frontiers in Immunology, 2021, 卷号: 12
Authors:  Miao, Lele;  Zhang, Zhengchao;  Ren, Zhijian;  Tang, Futian;  Li, Yumin
Adobe PDF(2696Kb)  |  Favorite  |    Submit date:2021/06/17
chimeric antigen receptor T cellimmunotherapyobstaclescoping strategiessolid tumors  
A new format of single chain tri-specific antibody with diminished molecular size efficiently induces ovarian tumor cell killing 期刊论文
BIOTECHNOLOGY LETTERS, 2005, 卷号: 27, 期号: 22, 页码: 1821-1827
Authors:  Liu, J;  Zhao, Q;  Zhao, BF;  Cheng, JL;  Wang, XB;  Song, LP;  Zhong, Z;  Lin, Q;  Huang, HL;  Huang, HL (reprint author), Chinese Acad Sci, Inst Genet & Dev Biol, Datun Rd, Beijing 100101, Peoples R China....Liu, J;  Zhao, Q;  Zhao, BF;  Cheng, JL;  Wang, XB;  Song, LP;  Zhong, Z;  Lin, Q;  Huang, HL;  Huang, HL (reprint author), Chinese Acad Sci, Inst Genet & Dev Biol, Datun Rd, Beijing 100101, Peoples R China.
Adobe PDF(268Kb)  |  Favorite  |    Submit date:2015/12/14
human CD3  immunotherapy  ovarian cancer  single chain tri-specific antibody  variable region of heavy chain  
通用有机磷、喜树碱单克隆抗体的制备及免疫检测技术研究 学位论文
硕士, 兰州: 兰州大学, 2015
Authors:  闫莉婷
Favorite  |    Submit date:2019/01/18
有机磷  喜树碱  人工抗原  单克隆抗体  单链抗体