兰州大学机构库

Browse/Search Results:  1-10 of 226 Help

Selected(0)Clear Items/Page:    Sort:
Protein structure prediction provides comparable performance to crystallographic structures in docking-based virtual screening 期刊论文
METHODS, 2015, 卷号: 71, 页码: 77-84
Authors:  Du, HY;  Brender, JR;  Zhang, J;  Zhang, Y;  Zhang, Y (reprint author), Univ Michigan, Dept Computat Med & Bioinformat, 100 Washtenaw Ave, Ann Arbor, MI 48109 USA.
Adobe PDF(1995Kb)  |  Favorite  |    Submit date:2015/12/23
Virtual screening  Enrichment rate  Ligand docking  Protein structure prediction  
Search for beta(2) Adrenergic Receptor Ligands by Virtual Screening via Grid Computing and Investigation of Binding Modes by Docking and Molecular Dynamics Simulations 期刊论文
PLoS One, 2014, 卷号: 9, 期号: 9, 页码: -
Authors:  Bai, QF;  Shao, YH;  Pan, DB;  Zhang, Y;  Liu, HX;  Yao, XJ(姚小军);  Yao, XJ (reprint author), Lanzhou Univ, Dept Chem, Lanzhou 730000, Peoples R China.
Adobe PDF(2723Kb)  |  Favorite  |    Submit date:2015/05/21
Discovery of Novel Inhibitor for WNT/beta-Catenin Pathway by Tankyrase 1/2 Structure-Based Virtual Screening 期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 7
Authors:  Li, Bo;  Liang, Jinxia;  Lu, Feng;  Zeng, Guandi;  Zhang, Jindao;  Ma, Yinxing;  Liu, Peng;  Wang, Qin;  Zhou, Qian;  Chen, Liang...Li, Bo;  Liang, Jinxia;  Lu, Feng;  Zeng, Guandi;  Zhang, Jindao;  Ma, Yinxing;  Liu, Peng;  Wang, Qin;  Zhou, Qian;  Chen, Liang
Adobe PDF(4367Kb)  |  Favorite  |    Submit date:2020/07/13
tankyrase 1  2 inhibitors  WNT  beta-catenin signaling pathway  virtual screening  dock  antitumor  
Virtual screening and rational drug design method using structure generation system based on 3D-QSAR and docking 期刊论文
SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2003, 卷号: 14, 期号: 4
Authors:  Chen, HF;  Dong, XC;  Zen, BS;  Gao, K(高坤);  Yuan, SG;  Panaye, A;  Doucet, JP;  Fan, BT;  Fan, BT (reprint author), Univ Paris 07, CNRS UMR7086, ITODYS, 1 Rue Guy Brosse, F-75005 Paris, France.
Adobe PDF(413Kb)  |  Favorite  |    Submit date:2014/12/05
Drug Design  Structure Generation  3d-qsar  Docking  Virtual Screening  
A combination of pharmacophore modeling, virtual screening, and molecular docking studies for a diverse set of colchicine site inhibitors 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: 11, 页码: 4713-4723
Authors:  Li, HH;  Liu, T;  Xuan, HX;  Fang, SB;  Zhao, CY(赵春燕);  Zhao, CY (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
Adobe PDF(2251Kb)  |  Favorite  |    Submit date:2015/12/29
Colchicine binding site inhibitors  Pharmacophore  Virtual screening  Docking  
QSAR classification of estrogen receptor binders and pre-screening of potential pleiotropic EDCs 期刊论文
SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2010, 卷号: 21, 期号: 7-8
Authors:  Li, J;  Gramatica, P;  Gramatica, P (reprint author), Univ Insubria, QSAR Res Unit Environm Chem & Ecotoxicol, Dept Struct & Funct Biol, Varese, Italy.
Adobe PDF(301Kb)  |  Favorite  |    Submit date:2014/12/05
Estrogen Receptor (Er)  Androgen Receptor (Ar)  Pleiotropic Edc  External Validation  Virtual Screening  
Classification and Virtual Screening of Androgen Receptor Antagonists 期刊论文
Journal of Chemical Information and Modeling, 2010, 卷号: 50, 期号: 5
Authors:  Li, JZ;  Gramatica, P;  Gramatica, P (reprint author), Univ Insubria, Dept Struct & Funct Biol, QSAR Res Unit Environm Chem & Ecotoxicol, Via Dunant 3, I-21100 Varese, Italy.
Adobe PDF(1702Kb)  |  Favorite  |    Submit date:2014/12/05
Development of Cell-Active N-6-Methyladenosine RNA Demethylase FTO Inhibitor 期刊论文
Journal of the American Chemical Society, 2012, 卷号: 134, 期号: 43
Authors:  Chen, BE;  Ye, F;  Yu, L;  Jia, GF;  Huang, XT;  Zhang, XJ;  Peng, SY;  Chen, K;  Wang, MN;  Gong, SZ...Chen, BE;  Ye, F;  Yu, L;  Jia, GF;  Huang, XT;  Zhang, XJ;  Peng, SY;  Chen, K;  Wang, MN;  Gong, SZ;  Zhang, RH;  Yin, JY;  Li, HY;  Yang, YM;  Liu, H;  Zhang, JW;  Zhang, HY;  Zhang, A;  Jiang, HL;  Luo, C;  Yang, CG;  Luo, C (reprint author), Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China.
Adobe PDF(2736Kb)  |  Favorite  |    Submit date:2014/12/05
Brevilin A, a Novel Natural Product, Inhibits Janus Kinase Activity and Blocks STAT3 Signaling in Cancer Cells 期刊论文
PLoS One, 2013, 卷号: 8, 期号: 5, 页码: -
Authors:  Chen, X;  Du, YP;  Nan, J;  Zhang, XX;  Qin, XD;  Wang, YX;  Hou, JW;  Wang, Q;  Yang, JB(杨金波);  Yang, JB (reprint author), Lanzhou Univ, Sch Life Sci, Lanzhou 730000, Gansu, Peoples R China....Chen, X;  Du, YP;  Nan, J;  Zhang, XX;  Qin, XD;  Wang, YX;  Hou, JW;  Wang, Q;  Yang, JB(杨金波);  Yang, JB (reprint author), Lanzhou Univ, Sch Life Sci, Lanzhou 730000, Gansu, Peoples R China.
Adobe PDF(2984Kb)  |  Favorite  |    Submit date:2015/12/14