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兰州大学机构库

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GM-Pep: A High Efficiency Strategy to De Novo Design Functional Peptide Sequences 期刊论文
Journal of Chemical Information and Modeling, 2022, 卷号: 62, 期号: 10, 页码: 2617-2629
Authors:  Chen, Qushuo;  Yang, Changyan;  Xie, Yihao;  Wang, Yuqiang;  Li, Xiaoxu;  Wang, KR(王凯荣);  Huang, Jinqi;  Yan, WJ(阎文锦)
Favorite  |    Submit date：2022/07/01
Bioactivity  Drug interactions  Learning systems  Toxicity  Auto encoders  Computation methods  De novo design  Functional peptides  Higher efficiency  Multi-classifier  Peptide sequences  Peptide therapeutics  Therapeutic agents  Therapeutic peptides  
GM-Pep: A High Efficiency Strategy to de Novo Design Functional Peptide Sequences 期刊论文
Journal of Chemical Information and Modeling, 2022
Authors:  Chen, Qushuo;  Yang, Changyan;  Xie, Yihao;  Wang, Yuqiang;  Li, Xiaoxu;  Wang, KR(王凯荣);  Huang, Jinqi;  Yan, WJ(阎文锦)
Favorite  |    Submit date：2022/11/08
Bioactivity  Drug interactions  Learning systems  Toxicity  Auto encoders  Computation methods  De novo design  Functional peptides  Higher efficiency  Multi-classifier  Peptide sequences  Peptide therapeutics  Therapeutic agents  Therapeutic peptides  
Potent Antimicrobial and Antibiofilm Activities of Feleucin-K3 Analogs Modified by alpha-(4-Pentenyl)-Ala against Multidrug-Resistant Bacteria 期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 5
Authors:  Guo, Xiaomin;  Yan, Tiantian;  Rao, Jing;  Yue, Xin;  Pei, Xiong;  Deng, Jiahui;  Sun, Wangsheng;  Yang, Wenle;  Zhang, Bangzhi;  Xie, JQ(谢俊秋)...Guo, Xiaomin;  Yan, Tiantian;  Rao, Jing;  Yue, Xin;  Pei, Xiong;  Deng, Jiahui;  Sun, Wangsheng;  Yang, Wenle;  Zhang, Bangzhi;  Xie, JQ(谢俊秋)
Adobe PDF(5637Kb)  |  Favorite  |    Submit date：2021/06/17
antimicrobial peptide analogsunnatural hydrophobic amino acidalpha-(4-pentenyl)-Alaantimicrobial activityantibiofilm activity  
Multiple action mechanism and in vivo antimicrobial efficacy of antimicrobial peptide Jelleine-I 期刊论文
JOURNAL OF PEPTIDE SCIENCE, 2021, 卷号: 27, 期号: 3
Authors:  Jia, Fengjing;  Wang, Jiayi;  Zhang, Lishi;  Zhou, Jingjing;  He, Yuhang;  Lu, Yaqi;  Liu, Kexin;  Yan, WJ(阎文锦);  Wang, KR(王凯荣)
Adobe PDF(13051Kb)  |  Favorite  |    Submit date：2021/04/16
action mode  antimicrobial agent  antimicrobial peptide  Jelleine‐  I  
Tryptic Stability and Antimicrobial Activity of the Derivatives of Polybia-CP with Fine-Tuning Modification in the Side Chain of Lysine 期刊论文
International Journal of Peptide Research and Therapeutics, 2020
Authors:  Jia, Fengjing;  Liang, Xiaolei;  Wang, Jiayi;  Zhang, Lishi;  Zhou, Jingjing;  He, Yuhang;  Zhang, Fangfang;  Yan, WJ(阎文锦);  Wang, KR(王凯荣)
Adobe PDF(2182Kb)  |  Favorite  |    Submit date：2020/12/18
Cationic antimicrobial peptide  Polybia-CP  Tryptic stability  Fine-tuning of side chain  
组氨酸引入对抗菌肽的生物活性、构效关系及肽与金属离子相互作用的影响 学位论文
理学博士, 兰州: 兰州大学, 2020
Authors:  彭金秀
Favorite  |    Submit date：2021/12/06
抗菌肽  组氨酸  抗菌活性  稳定性  毒性  二级结构  Cu2+  Zn2+  
Cu2+ reduces hemolytic activity of the antimicrobial peptide HMPI and enhances its trypsin resistance 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2020, 卷号: 52, 期号: 6, 页码: 603-611
Authors:  Peng, Jinxiu;  Yang, Yang;  Zhao, Ping;  Qiu, Shuai;  Jia, Fengjing;  Wang, Jiayi;  Liang, Xiaolei;  Chaudhry, Ahmed Shabbir;  Xu, Peihan;  Yan, WJ(阎文锦)...Peng, Jinxiu;  Yang, Yang;  Zhao, Ping;  Qiu, Shuai;  Jia, Fengjing;  Wang, Jiayi;  Liang, Xiaolei;  Chaudhry, Ahmed Shabbir;  Xu, Peihan;  Yan, WJ(阎文锦);  Xu, ZQ(许兆青);  Wang, KR(王凯荣)
Adobe PDF(940Kb)  |  Favorite  |    Submit date：2020/12/20
antimicrobial peptide HMPI  antifungal activity  protease  stability  trypsin  
Toxicity and metabolism of 3-bromopyruvate in Caenorhabditis elegans 期刊论文
Journal of Zhejiang University-SCIENCE B, 2020, 卷号: 21, 期号: 1, 页码: 77-86
Authors:  Gu Qiaoling;  Zhang Yan;  Fu Ximei;  Lu Zhaolian;  Yu Yao;  Chen, G(陈根);  Ma Rong;  Kou Wei;  Lan Yongmei
Adobe PDF(719Kb)  |  Favorite  |    Submit date：2020/08/06
3-Bromopyruvate  Caenorhabditis elegans  Hexokinase  Cytochrome P450  
抗菌肽polybia-MPⅡ及其类似物抗菌活性、细胞毒性和酶解稳定性的研究 学位论文
硕士, 兰州: 兰州大学, 2019
Authors:  赵萍
Favorite  |    Submit date：2020/01/15
抗菌肽  polybia-MPⅡ  抗菌活性  酶解稳定性  溶血活性  
D型氨基酸替换和赖氨酸侧链微修饰对抗菌肽polybia-CP生物活性及稳定性的影响研究 学位论文
硕士, 兰州: 兰州大学, 2018
Authors:  汪嘉懿
Favorite  |    Submit date：2019/01/17
抗菌肽polybia-CP  D型氨基酸替换  赖氨酸侧链微修饰  抗菌活性  稳定性