兰州大学机构库

Browse/Search Results:  1-10 of 35 Help

Selected(0)Clear Items/Page:    Sort:
BACE1 gene silencing alleviates isoflurane anesthesia-induced postoperative cognitive dysfunction in immature rats by activating the PI3K/Akt signaling pathway 期刊论文
Molecular Medicine Reports, 2018, 卷号: 18, 期号: 5, 页码: 4259-4270
Authors:  Wang, Ying-Bin;  Xie, JQ(谢建琴);  Liu, Wei;  Zhang, Rong-Zhi;  Huang, Sheng-Hui;  Xing, Yan-Hong
Favorite  |    Submit date:2019/10/31
beta-site amyloid precursor protein cleavage enzyme 1  gene silencing  phosphatidylinositol-3-kinase/protein kinase B signaling pathway  isoflurane anesthesia  amyloid precursor protein  beta-amyloid  postoperative cognitive dysfunction  
Stabilities and structures of islet amyloid polypeptide (IAPP(22-28)) oligomers: From dimer to 16-mer 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2014, 卷号: 1840, 期号: 1, 页码: 357-366
Authors:  Guo, Jingjing;  Zhang, Yan;  Ning, Lulu;  Jiao, Pingzu;  Liu, HX(刘焕香);  Yao, XJ(姚小军)
Adobe PDF(2733Kb)  |  Favorite  |    Submit date:2015/12/29
Nucleation  Amyloid fibril  Molecular dynamics simulation  Islet amyloid polypeptide (residues 22-28)  Type II diabetes  
脊髓背角APLP2在神经病理性疼痛中的作用 学位论文
药学硕士, 兰州: 兰州大学, 2023
Authors:  朱阅宾
Favorite  |    Submit date:2023/11/15
APLP2  amyloid precursor-like protein 2  外周神经损伤  peripheral nerve injury  痛觉超敏  allodynia  痛觉过敏  hyperalgesia  小胶质细胞  microglia  神经病理性疼痛  neuropathic pain  
Synergistic effects of hIAPP and A beta(1-42) impaired the olfactory function associated with the decline of adult neurogenesis in SVZ 期刊论文
NEUROPEPTIDES, 2022, 卷号: 96
Authors:  Chen, Hai-Chao;  Ma, Yue-Zhang;  Cao, Jia-Xin;  Zhang, Yi-Shu;  Zhang, Lu;  Gao, LP(高丽萍);  Jing, YH(景玉宏)
Favorite  |    Submit date:2022/11/09
Human islet amyloid polypeptide  A beta(1-42)  Olfactory bulb  Adult neural stem cell  Subventricular zone  
Alterations in amyloid beta-protein and apolipoprotein E in cerebrospinal fluid after subarachnoid hemorrhage 期刊论文
Neural Regeneration Research, 2007, 卷号: 2, 期号: 3, 页码: 151-155
Authors:  Xinzhong Wen;  Yonghong Zhang;  Leiming Huo
Favorite  |    Submit date:2016/09/12
subarachnoid hemorrhage  amyloid beta-protein  apolipoprotein E  erebrospinal fluid  
High-Fat Diet Increases Amylin Accumulation in the Hippocampus and Accelerates Brain Aging in hIAPP Transgenic Mice 期刊论文
Frontiers in Aging Neuroscience, 2019, 卷号: 11
Authors:  Xi, XX(席晓霞);  Sun, J(孙婧);  Chen, Hai-Chao;  Chen, An-Di;  Gao, LP(高丽萍);  Yin, J(尹洁);  Jing, YH(景玉宏)
Favorite  |    Submit date:2019/10/10
human islet amyloid polypeptide  high-fat diet  hippocampus  cognition  brain aging  
Interaction of human IAPP and A beta(1-42) aggravated the AD-related pathology and impaired the cognition in mice 期刊论文
EXPERIMENTAL NEUROLOGY, 2020, 卷号: 334
Authors:  Chen, Hai-Chao;  Cao, Jia-Xin;  Cai, Yi-Ting;  Du, Hong-Li;  Xi, Xiao-Xia;  Sun, Jing;  Yin, J(尹洁);  Gao, LP(高丽萍);  Jing, YH(景玉宏)
Favorite  |    Submit date:2020/12/20
Human islet amyloid polypeptide (hIAPP)  A beta(1-42)  Hippocampus  Mitochondrial stress  Cognition impairment  
Exploring the effect of silicene monolayer on the structure and function of villin headpiece and amyloid fibrils by molecular dynamics simulations 期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2020, 卷号: 89, 期号: 1, 页码: 107-115
Authors:  Meng, Yajie;  Liu, Ruirui;  Song, Liting;  Zhu, Min;  Zhai, HL(翟红林);  Ren, CL(任翠领)
Favorite  |    Submit date:2020/12/20
amyloid fibrils  function  HP35  molecular dynamics simulation  silicene monolayer  structure  
Endosomal pH favors shedding of membrane-inserted amyloid-beta peptide 期刊论文
PROTEIN SCIENCE, 2019, 卷号: 28, 期号: 5, 页码: 889-899
Authors:  Shi, Jing-Ming;  Lv, Jian-Min;  Gao, Bo-Xuan;  Zhang, Lin;  Ji, SR(吉尚戎)
Favorite  |    Submit date:2019/10/18
Alzheimer's disease  amyloid-beta peptide  Langmuir film balance  membrane insertion  shedding  
OLFML2A对胶质瘤细胞增殖与凋亡的影响及其机制研究 学位论文
医学硕士, 兰州: 兰州大学, 2021
Authors:  马世泽
Favorite  |    Submit date:2021/12/06
OLFML2A (Olfactomedin-like 2A )  胶质瘤  淀粉样前体蛋白 (amyloid precursor protein, APP)  增殖  凋亡  Wnt/β-catenin 信号通路