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兰州大学机构库
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Structure-Activity Relationship Study of Antimicrobial Peptide PE2 Delivered Novel Linear Derivatives with Potential of Eradicating Biofilms and Low Incidence of Drug Resistance 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 13, 页码: 8526-8544
Authors:  Zhang, Jingying;  Ouyang, Xu;  Zhang, Fangyan;  Li, Beibei;  Chang, Linlin;  Yang, Ping;  Mao, Wenbo;  Gou, SH(缑三虎);  Zhang, Y(张云);  Liu, H(刘晖)...Zhang, Jingying;  Ouyang, Xu;  Zhang, Fangyan;  Li, Beibei;  Chang, Linlin;  Yang, Ping;  Mao, Wenbo;  Gou, SH(缑三虎);  Zhang, Y(张云);  Liu, H(刘晖);  Yao, Jia;  Ni, JM(倪京满)
Favorite  |    Submit date：2023/09/04
One New Acid-Activated Hybrid Anticancer Peptide by Coupling with a Desirable pH-Sensitive Anionic Partner Peptide 期刊论文
ACS OMEGA, 2023
Authors:  Chang, Linlin;  Wu, Xiaoyan;  Ran, Kaixin;  Tian, Yali;  Ouyang, Xu;  Liu, H(刘晖);  Gou, Sanhu;  Zhang, Y(张云);  Ni, JM(倪京满)
Favorite  |    Submit date：2023/04/12
Short, mirror-symmetric antimicrobial peptides centered on ?RRR? have broad-spectrum antibacterial activity with low drug resistance and toxicity 期刊论文
ACTA BIOMATERIALIA, 2022, 卷号: 154, 页码: 145-167
Authors:  Zhang, Fangyan;  Yang, Ping;  Mao, Wenbo;  Zhong, Chao;  Zhang, Jingying;  Chang, Linlin;  Wu, Xiaoyan;  Liu, H(刘晖);  Zhang, Y(张云);  Gou, Sanhu...Zhang, Fangyan;  Yang, Ping;  Mao, Wenbo;  Zhong, Chao;  Zhang, Jingying;  Chang, Linlin;  Wu, Xiaoyan;  Liu, H(刘晖);  Zhang, Y(张云);  Gou, Sanhu;  Ni, JM(倪京满)
Favorite  |    Submit date：2023/02/22
Antimicrobial peptides  Mirror -symmetric structure  Bacterial resistance  Multiple mechanisms  In vitro and in vivo  
临床药学概论课程思政教学初步探讨 期刊论文
中国继续医学教育, 2022, 卷号: 14, 期号: 14, 页码: 172-176
Authors:  史彦斌;  刘晖;  张云;  田金徽;  杨飞;  李雪峰
Favorite  |    Submit date：2022/11/08
课程思政  德才兼备  临床药学  教学设计  评价方法  协同效应  教育  
Constructing new acid-activated anticancer peptide by attaching a desirable anionic binding partner peptide 期刊论文
JOURNAL OF DRUG TARGETING, 2022
Authors:  Zhang, Y(张云);  Chang, Linlin;  Bao, Hexin;  Wu, Xiaoyan;  Liu, H(刘晖);  Gou, Sanhu;  Zhang, Jingying;  Ni, JM(倪京满)
Favorite  |    Submit date：2022/07/01
Anticancer peptide  anionic binding partner  acid activated  low toxicity  enzymatic stability  
Novel beta-Hairpin Antimicrobial Peptides Containing the beta-Turn Sequence of -RRRF- Having High Cell Selectivity and Low Incidence of Drug Resistance br 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 7, 页码: 5625-5641
Authors:  Li, Beibei;  Ouyang, Xu;  Ba, Zufang;  Yang, Yinyin;  Zhang, Jingying;  Liu, H(刘晖);  Zhang, Tianyue;  Zhang, Fangyan;  Zhang, Y(张云);  Gou, Sanhu...Li, Beibei;  Ouyang, Xu;  Ba, Zufang;  Yang, Yinyin;  Zhang, Jingying;  Liu, H(刘晖);  Zhang, Tianyue;  Zhang, Fangyan;  Zhang, Y(张云);  Gou, Sanhu;  Ni, JM(倪京满)
Favorite  |    Submit date：2022/07/01
Novel synovial targeting peptide-sinomenine conjugates as a potential strategy for the treatment of rheumatoid arthritis 期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2022, 卷号: 617
Authors:  Zhang, Tianyue;  Ouyang, Xu;  Gou, Sanhu;  Zhang, Y(张云);  Yan, N(燕娜);  Chang, Linlin;  Li, Beibei;  Zhang, Fangyan;  Liu, H(刘晖);  Ni, JM(倪京满)...Zhang, Tianyue;  Ouyang, Xu;  Gou, Sanhu;  Zhang, Y(张云);  Yan, N(燕娜);  Chang, Linlin;  Li, Beibei;  Zhang, Fangyan;  Liu, H(刘晖);  Ni, JM(倪京满)
Favorite  |    Submit date：2022/07/01
Peptide-drug conjugates  Sinomenine  Rheumatoid arthritis  Target delivery  
Novel Broad-Spectrum Antimicrobial Peptide Derived from Anoplin and Its Activity on Bacterial Pneumonia in Mice 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 11247-11266
Authors:  Gou, Sanhu;  Li, Beibei;  Ouyang, Xu;  Ba, Zufang;  Zhong, Chao;  Zhang, Tianyue;  Chang, LinLin;  Zhu, Yuewen;  Zhang, Jingying;  Zhu, Ningyi...Gou, Sanhu;  Li, Beibei;  Ouyang, Xu;  Ba, Zufang;  Zhong, Chao;  Zhang, Tianyue;  Chang, LinLin;  Zhu, Yuewen;  Zhang, Jingying;  Zhu, Ningyi;  Zhang, Y(张云);  Liu, H(刘晖);  Ni, JM(倪京满)
Favorite  |    Submit date：2021/12/15
Antimicrobial peptides with symmetric structures against multidrug-resistant bacteria while alleviating antimicrobial resistance 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 186
Authors:  Zhong, Chao;  Zhang, Fangyan;  Yao, Jia;  Zhu, Yuewen;  Zhu, Ningyi;  Zhang, Y(张云);  Liu, H(刘晖);  Gou, Sanhu;  Ni, JM(倪京满)
Favorite  |    Submit date：2021/06/17
Antimicrobial peptidesAntimicrobial activityAnti-resistanceMultidrug-resistant bacteriaBiocompatibilityMultiple mechanisms  
New designed pH-responsive histidine-rich peptides with antitumor activity 期刊论文
JOURNAL OF DRUG TARGETING, 2021
Authors:  Chang, Linlin;  Bao, Hexin;  Yao, Jia;  Liu, H(刘晖);  Gou, Sanhu;  Zhong, Chao;  Zhang, Y(张云);  Ni, JM(倪京满)
Favorite  |    Submit date：2021/04/16
Histidine-rich peptide  acid-activatable  antitumor  high efficiency  low toxicity