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牦牛胶原蛋白-羟基磷灰石-海藻酸钠3D支架高效修复骨缺损
期刊论文
中国科学. 化学, 2023, 卷号: 53, 期号: 09, 页码: 1750-1760
Authors:
何会霞
;
王莉莉
;
蔡向东
;
李文华
;
肖建喜
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  |  
  
Submit date:2023/11/23
牦牛骨胶原蛋白
生物矿化
骨再生
组织工程
Application of computational approaches in biomembranes: From structure to function
期刊论文
Wiley Interdisciplinary Reviews-Computational Molecular Science, 2023
Authors:
Guo, Jingjing
;
Bao, Yiqiong
;
Li, Mengrong
;
Li, Shu
;
Xi, Lili
;
Xin, Pengyang
;
Wu, Lei
;
Liu, Huanxiang
;
Mu, Yuguang
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  |  
  
Submit date:2023/11/28
biological membranes
lipids
membrane proteins
molecular dynamics simulation
molecular modeling
(2E)-1-(2,4,6-Trimethoxyphenyl)-3-(4-chlorophenyl)prop-2-en-1-one, a Chalcone Derivative, Promotes Apoptosis by Suppressing RAS-ERK and AKT/FOXO3a Pathways in Hepatocellular Carcinoma Cells
期刊论文
CHEMISTRY & BIODIVERSITY, 2023
Authors:
Zhang, Meigui
;
Li, Jing
;
Ma, Ruixia
;
Xi, Jiahui
;
Xi, Lili
;
Zhang, Baoxin
;
Tian, Jing
;
Bai, Zhongtian
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  |  
  
Submit date:2023/11/28
chalcone derivative
apoptosis
ERK
MAPK pathway
AKT
FOXO3a signaling pathway
hepatocellular carcinoma
Licraside as novel potent FXR agonist for relieving cholestasis: structure-based drug discovery and biological evaluation studies
期刊论文
Frontiers in Pharmacology, 2023, 卷号: 14
Authors:
Xi, Lili
;
Shi, Axi
;
Shen, Tiantian
;
Wang, Guoxu
;
Wei, Yuhui
;
Guo, Jingjing
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Submit date:2023/11/28
FXR
licraside
agonist
cholestasis
virtual screening
biological evaluation
兰州地区22161例人群维生素D水平与性别、年龄、季节、日照时数和平均气温关系的回顾性研究
期刊论文
中国骨质疏松杂志, 2023, 卷号: 29, 期号: 06, 页码: 840-846
Authors:
孙晶晶
;
卢文雅
;
牛彩云
;
张巧梅
;
姚立琼
;
席莉莉
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  |  
  
Submit date:2023/07/18
25羟维生素D
维生素D缺乏
日照时数
平均气温
Computational Insights into the Allosteric Modulation of a Phthalate-Degrading Hydrolase by Distal Mutations
期刊论文
BIOMOLECULES, 2023, 卷号: 13, 期号: 3
Authors:
Xu, Ran
;
Bao, Yiqiong
;
Li, Mengrong
;
Zhang, Yan
;
Xi, Lili
;
Guo, Jingjing
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Submit date:2023/05/25
esterases
phthalate esters
rational design of proteins
distal mutations
molecular dynamics simulation
toxicity
Understanding the Allosteric Modulation of PTH1R by a Negative Allosteric Modulator
期刊论文
CELLS, 2023, 卷号: 12, 期号: 1
Authors:
Li, Mengrong
;
Bao, Yiqiong
;
Xu, Ran
;
Li, Miaomiao
;
Xi, Lili
;
Guo, Jingjing
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Submit date:2023/02/22
class B GPCR
parathyroid hormone type 1 receptor
negative allosteric modulator
molecular dynamics simulation
allosteric regulation
淫羊藿素通过线粒体通路增强索拉非尼的诱导凋亡作用(英文)
期刊论文
Journal of Chinese Pharmaceutical Sciences, 2022, 页码: 1-12
Authors:
石阿茜
;
沈阗阗
;
夏文彬
;
席莉莉
;
王利军
;
魏玉辉
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  |  
  
Submit date:2023/01/03
索拉非尼
淫羊藿素
人肝癌细胞
基于大鼠血清胆酸盐水平构建药物性肝损伤随机森林分类模型(英文)
期刊论文
Journal of Chinese Pharmaceutical Sciences, 2022, 卷号: 31, 期号: 09, 页码: 677-688
Authors:
靳永文
;
席莉莉
;
魏玉辉
;
武新安
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Submit date:2022/11/08
药物性肝损伤
胆酸盐
随机森林
基于肝药酶CYP3A4、SULT2A1和UGT1A1探究京尼平的代谢解毒路径(英文)
期刊论文
Journal of Chinese Pharmaceutical Sciences, 2022, 卷号: 31, 期号: 08, 页码: 608-621
Authors:
张帆
;
王晓慧
;
Abdulaziz Ahmed A.Saad
;
席莉莉
;
马小花
;
石阿茜
;
魏玉辉
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  |  
  
Submit date:2022/11/08
京尼平
代谢解毒
CYP3A4
SULT2A1
UGT1A1
栀子