兰州大学机构库

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牦牛胶原蛋白-羟基磷灰石-海藻酸钠3D支架高效修复骨缺损 期刊论文
中国科学. 化学, 2023, 卷号: 53, 期号: 09, 页码: 1750-1760
Authors:  何会霞;  王莉莉;  蔡向东;  李文华;  肖建喜
Favorite  |    Submit date:2023/11/23
牦牛骨胶原蛋白  生物矿化  骨再生  组织工程  
Application of computational approaches in biomembranes: From structure to function 期刊论文
Wiley Interdisciplinary Reviews-Computational Molecular Science, 2023
Authors:  Guo, Jingjing;  Bao, Yiqiong;  Li, Mengrong;  Li, Shu;  Xi, Lili;  Xin, Pengyang;  Wu, Lei;  Liu, Huanxiang;  Mu, Yuguang
Favorite  |    Submit date:2023/11/28
biological membranes  lipids  membrane proteins  molecular dynamics simulation  molecular modeling  
(2E)-1-(2,4,6-Trimethoxyphenyl)-3-(4-chlorophenyl)prop-2-en-1-one, a Chalcone Derivative, Promotes Apoptosis by Suppressing RAS-ERK and AKT/FOXO3a Pathways in Hepatocellular Carcinoma Cells 期刊论文
CHEMISTRY & BIODIVERSITY, 2023
Authors:  Zhang, Meigui;  Li, Jing;  Ma, Ruixia;  Xi, Jiahui;  Xi, Lili;  Zhang, Baoxin;  Tian, Jing;  Bai, Zhongtian
Favorite  |    Submit date:2023/11/28
chalcone derivative  apoptosis  ERK  MAPK pathway  AKT  FOXO3a signaling pathway  hepatocellular carcinoma  
Licraside as novel potent FXR agonist for relieving cholestasis: structure-based drug discovery and biological evaluation studies 期刊论文
Frontiers in Pharmacology, 2023, 卷号: 14
Authors:  Xi, Lili;  Shi, Axi;  Shen, Tiantian;  Wang, Guoxu;  Wei, Yuhui;  Guo, Jingjing
Favorite  |    Submit date:2023/11/28
FXR  licraside  agonist  cholestasis  virtual screening  biological evaluation  
兰州地区22161例人群维生素D水平与性别、年龄、季节、日照时数和平均气温关系的回顾性研究 期刊论文
中国骨质疏松杂志, 2023, 卷号: 29, 期号: 06, 页码: 840-846
Authors:  孙晶晶;  卢文雅;  牛彩云;  张巧梅;  姚立琼;  席莉莉
Favorite  |    Submit date:2023/07/18
25羟维生素D  维生素D缺乏  日照时数  平均气温  
Computational Insights into the Allosteric Modulation of a Phthalate-Degrading Hydrolase by Distal Mutations 期刊论文
BIOMOLECULES, 2023, 卷号: 13, 期号: 3
Authors:  Xu, Ran;  Bao, Yiqiong;  Li, Mengrong;  Zhang, Yan;  Xi, Lili;  Guo, Jingjing
Favorite  |    Submit date:2023/05/25
esterases  phthalate esters  rational design of proteins  distal mutations  molecular dynamics simulation  toxicity  
Understanding the Allosteric Modulation of PTH1R by a Negative Allosteric Modulator 期刊论文
CELLS, 2023, 卷号: 12, 期号: 1
Authors:  Li, Mengrong;  Bao, Yiqiong;  Xu, Ran;  Li, Miaomiao;  Xi, Lili;  Guo, Jingjing
Adobe PDF(4070Kb)  |  Favorite  |    Submit date:2023/02/22
class B GPCR  parathyroid hormone type 1 receptor  negative allosteric modulator  molecular dynamics simulation  allosteric regulation  
淫羊藿素通过线粒体通路增强索拉非尼的诱导凋亡作用(英文) 期刊论文
Journal of Chinese Pharmaceutical Sciences, 2022, 页码: 1-12
Authors:  石阿茜;  沈阗阗;  夏文彬;  席莉莉;  王利军;  魏玉辉
Favorite  |    Submit date:2023/01/03
索拉非尼  淫羊藿素  人肝癌细胞  
基于大鼠血清胆酸盐水平构建药物性肝损伤随机森林分类模型(英文) 期刊论文
Journal of Chinese Pharmaceutical Sciences, 2022, 卷号: 31, 期号: 09, 页码: 677-688
Authors:  靳永文;  席莉莉;  魏玉辉;  武新安
Favorite  |    Submit date:2022/11/08
药物性肝损伤  胆酸盐  随机森林  
基于肝药酶CYP3A4、SULT2A1和UGT1A1探究京尼平的代谢解毒路径(英文) 期刊论文
Journal of Chinese Pharmaceutical Sciences, 2022, 卷号: 31, 期号: 08, 页码: 608-621
Authors:  张帆;  王晓慧;  Abdulaziz Ahmed A.Saad;  席莉莉;  马小花;  石阿茜;  魏玉辉
Favorite  |    Submit date:2022/11/08
京尼平  代谢解毒  CYP3A4  SULT2A1  UGT1A1  栀子