兰州大学机构库

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VP3 G–H环中氨基酸突变对O型口蹄疫病毒生物学特性的影响 期刊论文
微生物学报, 2019, 卷号: 59, 期号: 07, 页码: 1285-1294
Authors:  陈冬冬;  白兴文;  宫晓华;  包慧芳;  李平花;  李冬;  付元芳;  白启峰;  袁红;  孙普...陈冬冬;  白兴文;  宫晓华;  包慧芳;  李平花;  李冬;  付元芳;  白启峰;  袁红;  孙普;  马雪青;  曹轶梅;  陈应理;  卢曾军;  刘在新
Favorite  |    Submit date:2023/11/22
口蹄疫病毒  VP3  G–H环  定点突变体  生物学特性  内吞作用  G-H环  
Engineering viable foot-and-mouth disease viruses with increased acid stability facilitate the development of improved vaccines 期刊论文
Applied Microbiology and Biotechnology, 2020, 卷号: 104, 期号: 4, 页码: 1683-1694
Authors:  Yuan, Hong;  Li, Pinghua;  Bao, Huifang;  Sun, Pu;  Bai, Xingwen;  Bai, QF(白启峰);  Li, N(李娜);  Ma, Xueqing;  Cao, Yimei;  Fu, Yuanfang...Yuan, Hong;  Li, Pinghua;  Bao, Huifang;  Sun, Pu;  Bai, Xingwen;  Bai, QF(白启峰);  Li, N(李娜);  Ma, Xueqing;  Cao, Yimei;  Fu, Yuanfang;  Li, Kun;  Zhang, Jing;  Li, Dong;  Chen, Yingli;  Zhang, Jie;  Lu, Zengjun;  Liu, Zaixin
Adobe PDF(4686Kb)  |  Favorite  |    Submit date:2020/08/04
FMDV  Vaccines  Acid stability  Substitution  
Studying noncovalent or covalent bond problem between smoothened and cholesterol by molecular dynamics simulation and Markov state model 期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2022, 卷号: 24, 期号: 32, 页码: 19564-19575
Authors:  Feng, Liya;  Pérez-Sánchez, Horacio;  Bai, QF(白启峰)
Favorite  |    Submit date:2022/11/08
Covalent bonds  Crystal structure  Free energy  Molecular dynamics  Bond problem  Crystals structures  Dynamics simulation  Free energy landscape  Malignant tumors  Markov State models  Noncovalent  Noncovalent bond  Simulated results  Therapeutic targets  
Deep Learning in COVID-19 Diagnosis, Prognosis and Treatment Selection 期刊论文
MATHEMATICS, 2023, 卷号: 11, 期号: 6
Authors:  Jin, Suya;  Liu, Guiyan;  Bai, QF(白启峰)
Favorite  |    Submit date:2023/05/25
artificial intelligence  deep learning  multi-modal learning  COVID-19  
WADDAICA: A webserver for aiding protein drug design by artificial intelligence and classical algorithm 期刊论文
Computational and Structural Biotechnology Journal, 2021, 卷号: 19, 页码: 3573-3579
Authors:  Bai, QF(白启峰);  Ma, Jian;  Liu, Shuo;  Xu, Tingyang;  Banegas-Luna, Antonio Jesús;  Pérez-Sánchez, Horacio;  Tian, Yanan;  Huang, Junzhou;  Liu, HX(刘焕香);  Yao, XJ(姚小军)...Bai, QF(白启峰);  Ma, Jian;  Liu, Shuo;  Xu, Tingyang;  Banegas-Luna, Antonio Jesús;  Pérez-Sánchez, Horacio;  Tian, Yanan;  Huang, Junzhou;  Liu, HX(刘焕香);  Yao, XJ(姚小军)
Favorite  |    Submit date:2021/12/14
Deeplearning  HTTP  Learningalgorithms  Candesign  ClassDGPCR  Classicalalgorithm  Deeplearning  DrugDesign  Learningmodels  Proteindrugs  Scaffoldhopping  Scoringpower  Webservers  
Computational Insight Into the Small Molecule Intervening PD-L1 Dimerization and the Potential Structure-Activity Relationship 期刊论文
Frontiers in Chemistry, 2019, 卷号: 7
Authors:  Shi, Danfeng;  An, Xiaoli;  Bai, QF(白启峰);  Bing, Zhitong;  Zhou, Shuangyan;  Liu, HX(刘焕香);  Yao, XJ(姚小军)
Favorite  |    Submit date:2020/08/20
PD-L1  small-molecule inhibitors  molecular dynamics simulation  metadynamics simulation  R-group QSAR  
Application advances of deep learning methods for de novo drug design and molecular dynamics simulation 期刊论文
Wiley Interdisciplinary Reviews-Computational Molecular Science, 2022, 卷号: 12, 期号: 3
Authors:  Bai, QF(白启峰);  Liu, Shuo;  Tian, Yanan;  Xu, Tingyang;  Banegas-Luna, Antonio Jesús;  Pérez-Sánchez, Horacio;  Huang, Junzhou;  Liu, HX(刘焕香);  Yao, XJ(姚小军)
Favorite  |    Submit date:2022/11/08
Computational chemistry  Learning systems  Ligands  Deep learning  Design  De novo drug design  Deep learning  Drug Design  Drug discovery  Explainable artificial intelligence  Interaction mechanisms  Interpretable machine learning  Learning methods  Molecular force field  Novel ligands  
MolAICal: a soft tool for 3D drug design of protein targets by artificial intelligence and classical algorithm 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 3
Authors:  Bai, QF(白启峰);  Tan, Shuoyan;  Xu, Tingyang;  Liu, HX(刘焕香);  Huang, Junzhou;  Yao, XJ(姚小军)
Favorite  |    Submit date:2021/12/15
drug design  virtual screening  de novo drug design  artificial intelligence  GCGR  SARS-CoV-2 main protease  
Computational studies on horseshoe shape pocket of human orexin receptor type 2 and boat conformation of suvorexant by molecular dynamics simulations 期刊论文
Chemical Biology & Drug Design, 2018, 卷号: 92, 期号: 1, 页码: 1221-1231
Authors:  Bai, QF(白启峰);  Perez-Sanchez, Horacio;  Shi, Zhuoyu;  Li, Lanlan;  Shi, Danfeng;  Liu, Huanxiang;  Yao, Xiaojun
Favorite  |    Submit date:2019/11/05
GPCR  human orexin receptor type 2  MMGBSA  molecular dynamics simulations  QM  MM  
Drug repositioning in drug discovery of T2DM and repositioning potential of antidiabetic agents 期刊论文
Computational and Structural Biotechnology Journal, 2022, 卷号: 20, 页码: 2839-2847
Authors:  Zhu, Sha;  Bai, QF(白启峰);  Li, Lanqing;  Xu, Tingyang
Favorite  |    Submit date:2022/11/08
Neurodegenerative diseases  Antidiabetic agents  Antidiabetic drug  Deep learning  Drug discovery  Drug repositioning  Drug repurposing  Machine learning methods  Market potential  Repurposing  Type 2 diabetes mellitus