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Constructing new acid-activated anticancer peptide by attaching a desirable anionic binding partner peptide
期刊论文
JOURNAL OF DRUG TARGETING, 2022
Authors:
Zhang, Y(张云)
;
Chang, Linlin
;
Bao, Hexin
;
Wu, Xiaoyan
;
Liu, H(刘晖)
;
Gou, Sanhu
;
Zhang, Jingying
;
Ni, JM(倪京满)
Favorite
  |  
  
Submit date:2022/07/01
Anticancer peptide
anionic binding partner
acid activated
low toxicity
enzymatic stability
酸敏感抗癌组合肽的设计、合成及抗肿瘤活性研究
学位论文
医学硕士, 兰州: 兰州大学, 2021
Authors:
鲍赫鑫
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  |  
  
Submit date:2021/12/06
抗癌肽
肿瘤酸性微环境
抗肿瘤
pH靶向
低毒
Late Quaternary Fault Slip Rate Within the Qilian Orogen, Insight Into the Deformation Kinematics for the NE Tibetan Plateau
期刊论文
TECTONICS, 2021, 卷号: 40, 期号: 5
Authors:
Hu, XF(胡小飞)
;
Cao, Xilin
;
Li, Tao
;
Mao, Junwei
;
Zhang, Jian
;
He, Xin
;
Zhang, Ya'nan
;
Pan, BT(潘保田)
Favorite
  |  
  
Submit date:2021/06/17
active faultcrust shorteningfluvial terraceQilian Shanslip rate
Deformation
Kinematics
Luminescence
Crustalshortening
Deformationrates
Fault
sliprates
Fieldinvestigation
Fluvialterraces
Modelevaluation
Netibetanplateaux
Opticallystimulatedluminescence
Newly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 卷号: 158
Authors:
Zhu, Ningyi
;
Zhong, Chao
;
Liu, Tianqi
;
Zhu, Yuewen
;
Gou, Sanhu
;
Bao, Hexin
;
Yao, Jia
;
Ni, Jingman
Favorite
  |  
  
Submit date:2021/04/16
Antimicrobial peptides
Cell selectivity
Antibiotic adjuvant
Rifampin
Rifampin-resistant Escherichia coli
Gram-negative bacteria
New designed pH-responsive histidine-rich peptides with antitumor activity
期刊论文
JOURNAL OF DRUG TARGETING, 2021
Authors:
Chang, Linlin
;
Bao, Hexin
;
Yao, Jia
;
Liu, H(刘晖)
;
Gou, Sanhu
;
Zhong, Chao
;
Zhang, Y(张云)
;
Ni, JM(倪京满)
Favorite
  |  
  
Submit date:2021/04/16
Histidine-rich peptide
acid-activatable
antitumor
high efficiency
low toxicity
Effect of N-methylated and fatty acid conjugation on analogs of antimicrobial peptide Anoplin
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020, 卷号: 152
Authors:
Liu, Tianqi
;
Zhu, Ningyi
;
Zhong, Chao
;
Zhu, Yuewen
;
Gou, Sanhu
;
Chang, Linlin
;
Bao, Hexin
;
Liu, Hui
;
Zhang, Yun
;
Ni, Jingman
...
Liu, Tianqi
;
Zhu, Ningyi
;
Zhong, Chao
;
Zhu, Yuewen
;
Gou, Sanhu
;
Chang, Linlin
;
Bao, Hexin
;
Liu, Hui
;
Zhang, Yun
;
Ni, Jingman
Favorite
  |  
  
Submit date:2020/12/20
Antimicrobial peptides
Anoplin
N-methyl amino acid
Fatty acid conjugation
Proteolytic stability
黄河兰州段河谷演化研究与认识
期刊论文
地球科学进展, 2020, 卷号: 35, 期号: 4, 页码: 404-413
Authors:
贺鑫
;
胡小飞
;
潘保田
Favorite
  |  
  
Submit date:2020/12/21
兰州盆地
阶地
河谷演化
黄河
Design of a new pH-activatable cell-penetrating peptide for drug delivery into tumor cells
期刊论文
Chemical Biology & Drug Design, 2019, 卷号: 94, 期号: 5, 页码: 1884-1893
Authors:
Zhang, Y(张云)
;
Li, Li
;
Chang, Linlin
;
Liu, H(刘晖)
;
Song, JJ(宋竟婧)
;
Liu, Yue
;
Bao, Hexin
;
Liu, Beijun
;
Wang, R(王锐)
;
Ni, JM(倪京满)
...
Zhang, Y(张云)
;
Li, Li
;
Chang, Linlin
;
Liu, H(刘晖)
;
Song, JJ(宋竟婧)
;
Liu, Yue
;
Bao, Hexin
;
Liu, Beijun
;
Wang, R(王锐)
;
Ni, JM(倪京满)
Favorite
  |  
  
Submit date:2020/08/20
acid-activated
anticancer drug delivery
cell-penetrating peptides
low cytotoxicity
pH-dependent antitumor activity
盗挖矿石发生伤亡事故应如何定性
期刊论文
人民检察, 2008, 期号: 11, 页码: 29-33
Authors:
袁保伟
;
陈航
;
张鹤新
;
韩东
;
许栋梁
;
孙永生
;
李苹
Favorite
  |  
  
Submit date:2016/07/22
重大责任事故罪:6121
重大劳动安全事故罪:5245
非法采矿罪:2925
重大伤亡事故:2924
犯罪主体:2296
矿石:1704
相似之处:1645
组织行为:1533
犯罪构成:1528
组织者:1525