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兰州大学机构库

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Design, synthesis, and biological evaluation of 1-styrenyl isoquinoline derivatives for anti-hepatocellular carcinoma activity and effect on mitochondria 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256
Authors:  Wang, Yuqing;  Long, Lin;  Zhuo, Linsheng;  Zhang, Honghua;  Luo, Tian;  Deng, Jiedan;  Wang, Yuying;  Li, Zhao;  Wang, Zhen;  Peng, Xue...Wang, Yuqing;  Long, Lin;  Zhuo, Linsheng;  Zhang, Honghua;  Luo, Tian;  Deng, Jiedan;  Wang, Yuying;  Li, Zhao;  Wang, Zhen;  Peng, Xue
Favorite  |    Submit date：2023/07/18
Hepatocellular carcinoma  Mitochondria  1-Styryl isoquinoline  Resveratrol  Apoptosis  
N(14)-substituted evodiamine derivatives as dual topoisomerase 1/tubuli- n-Inhibiting anti-gastrointestinal tumor agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 255
Authors:  Deng, Jiedan;  Long, Lin;  Peng, Xue;  Jiang, Weifan;  Peng, Ying;  Zhang, Xi;  Zhao, Yuting;  Tian, Ying;  Wang, Zhen;  Zhuo, Linsheng...Deng, Jiedan;  Long, Lin;  Peng, Xue;  Jiang, Weifan;  Peng, Ying;  Zhang, Xi;  Zhao, Yuting;  Tian, Ying;  Wang, Zhen;  Zhuo, Linsheng
Favorite  |    Submit date：2023/07/18
Top 1  tubulin inhibitor  Evodiamine derivatives  Anti -Tumor  
吴茱萸碱衍生物的高效合成及其抗肿瘤活性研究 学位论文
理学博士, 兰州: 兰州大学, 2023
Authors:  邓杰丹
Favorite  |    Submit date：2023/11/15
吴茱萸碱  Evodiamine  抗肿瘤  antitumor  构效关系  structure-activity relationship  拓扑异构酶 I  topoisomerase I  微管蛋白  tubulin  
Discovery of evodiamine derivatives as potential lead antifungal agents for the treatment of superficial fungal infections 期刊论文
BIOORGANIC CHEMISTRY, 2022, 卷号: 127
Authors:  Liang, Yan;  Zhang, Honghua;  Zhang, Xi;  Peng, Ying;  Deng, Jiedan;  Wang, Yuqing;  Li, Ranhui;  Liu, Linyi;  Wang, Z(王震)
Favorite  |    Submit date：2022/11/09
Evodiamine derivatives  Antifungal activity  Superficial fungal infections  
Discovery of evodiamine derivatives as potential lead antifungal agents for the treatment of superficial fungal infections 期刊论文
BIOORGANIC CHEMISTRY, 2022, 卷号: 127
Authors:  Liang, Yan;  Zhang, Honghua;  Zhang, Xi;  Peng, Ying;  Deng, Jiedan;  Wang, Yuqing;  Li, Ranhui;  Liu, Linyi;  Wang, Zhen
Favorite  |    Submit date：2022/11/09
Evodiamine derivatives  Antifungal activity  Superficial fungal infections  
Design, synthesis and bioactivity evaluation of favorable evodiamine derivative scaffold for developing cancer therapy 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239
Authors:  Liang, Ziyi;  Wang, Yuqing;  Zhang, Honghua;  Deng, Jiedan;  Lei, Fang;  Li, Junfang;  Shi, Tao;  Wang, Shuzhi;  Li, Ranhui;  Wang, Z(王震)...Liang, Ziyi;  Wang, Yuqing;  Zhang, Honghua;  Deng, Jiedan;  Lei, Fang;  Li, Junfang;  Shi, Tao;  Wang, Shuzhi;  Li, Ranhui;  Wang, Z(王震)
Favorite  |    Submit date：2022/11/09
Top1 and Top2 inhibitor  Evodiamine derivatives  Structure-activity relationships  Anti-cancer activity  
Design, synthesis and bioactivity evaluation of favorable evodiamine derivative scaffold for developing cancer therapy 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239
Authors:  Liang, Ziyi;  Wang, Yuqing;  Zhang, Honghua;  Deng, Jiedan;  Lei, Fang;  Li, Junfang;  Shi, Tao;  Wang, Shuzhi;  Li, Ranhui;  Wang, Zhen...Liang, Ziyi;  Wang, Yuqing;  Zhang, Honghua;  Deng, Jiedan;  Lei, Fang;  Li, Junfang;  Shi, Tao;  Wang, Shuzhi;  Li, Ranhui;  Wang, Zhen
Favorite  |    Submit date：2022/11/09
Top1 and Top2 inhibitor  Evodiamine derivatives  Structure-activity relationships  Anti-cancer activity  
Design, synthesis and bioactivity evaluation of novel N-phenyl-substituted evodiamine derivatives as potent anti-tumor agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 55
Authors:  Hao, Xiangyong;  Deng, Jiedan;  Zhang, Honghua;  Liang, Ziyi;  Lei, Fang;  Wang, Yuqing;  Yang, Xiaoyan;  Wang, Zhen
Favorite  |    Submit date：2022/04/20
PI3K  AKT  Evodiamine derivatives  Anti-tumor  
Design, synthesis and bioactivity evaluation of novel evodiamine derivatives with excellent potency against gastric cancer 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 228
Authors:  Liang, Ziyi;  Lei, Fang;  Deng, Jiedan;  Zhang, Honghua;  Wang, Yuqing;  Li, Junfang;  Shi, Tao;  Yang, Xiaoyan;  Wang, Zhen
Favorite  |    Submit date：2022/04/20
Top1 inhibitor  Evodiamine derivatives  Gastric cancer  
Design, synthesis and bioactivity study of evodiamine derivatives as multifunctional agents for the treatment of hepatocellular carcinoma 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114
Authors:  Fan, Xiaohong;  Deng, Jiedan;  Shi, Tao;  Wen, Huaixiu;  Li, Junfang;  Liang, Ziyi;  Lei, Fang;  Liu, Dan;  Zhang, Honghua;  Liang, Yan...Fan, Xiaohong;  Deng, Jiedan;  Shi, Tao;  Wen, Huaixiu;  Li, Junfang;  Liang, Ziyi;  Lei, Fang;  Liu, Dan;  Zhang, Honghua;  Liang, Yan;  Hao, Xiangyong;  Wang, Zhen
Favorite  |    Submit date：2021/12/15
Hepatocellular carcinoma  Topo I  Evodiamine  Cancer-associated fibroblasts (CAFs)