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Mechanism of ligusticum cycloprolactam against neuroinflammation based on network pharmacology and experimental verification
期刊论文
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2023, 卷号: 50, 期号: 8, 页码: 647-663
Authors:
Gao, Juan
;
Su, Gang
;
Chen, Wei
;
Wu, Qionghui
;
Liu, Junxi
;
Liu, Jifei
;
Chai, Miao
;
Dong, Ying
;
Wang, He
;
Chen, Lixia
...
Gao, Juan
;
Su, Gang
;
Chen, Wei
;
Wu, Qionghui
;
Liu, Junxi
;
Liu, Jifei
;
Chai, Miao
;
Dong, Ying
;
Wang, He
;
Chen, Lixia
;
Zhang, Zhenchang
;
Wang, Manxia
Favorite
  |  
  
Submit date:2023/07/18
BV2 microglia cells
HT22 cells
ligusticum cycloprolactam
network pharmacology
neuroinflammation
NF-kappa B
Targeting p53 for neuroinflammation: New therapeutic strategies in ischemic stroke
期刊论文
JOURNAL OF NEUROSCIENCE RESEARCH, 2023, 卷号: 101, 期号: 9, 页码: 1393-1408
Authors:
Gao, Juan
;
Liu, Jifei
;
Li, Yonghong
;
Liu, Junxi
;
Wang, He
;
Chai, Miao
;
Dong, Ying
;
Zhang, Zhenchang
;
Su, Gang
;
Wang, Manxia
...
Gao, Juan
;
Liu, Jifei
;
Li, Yonghong
;
Liu, Junxi
;
Wang, He
;
Chai, Miao
;
Dong, Ying
;
Zhang, Zhenchang
;
Su, Gang
;
Wang, Manxia
Favorite
  |  
  
Submit date:2023/07/18
ischemic stroke
neuroinflammation
p53
targeted therapy
Pharmacokinetics, tissue distribution, and safety evaluation of a ligustilide derivative (LIGc)
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 182
Authors:
Zhang, Yanxia
;
Zhang, Yaming
;
Han, Yanming
;
Tian, Ye
;
Wu, Pengcheng
;
Xin, Aiyi
;
Wei, Xiaoning
;
Shi, Yanbin
;
Zhang, Zhenchang
;
Su, Gang
...
Zhang, Yanxia
;
Zhang, Yaming
;
Han, Yanming
;
Tian, Ye
;
Wu, Pengcheng
;
Xin, Aiyi
;
Wei, Xiaoning
;
Shi, Yanbin
;
Zhang, Zhenchang
;
Su, Gang
;
Shi, Yanping
;
Liu, Junxi
Favorite
  |  
  
Submit date:2020/08/06
Ligustilide
LIGc
Pharmacokinetics
Tissue distribution
HPLC-DAD
Acute toxicity
Isocorydine induces cell differentiation through reversed epithelial mesenchymal transition in SiHa cells
期刊论文
International Journal of Clinical and Experimental Medicine, 2018, 卷号: 11, 期号: 8, 页码: 7811-+
Authors:
Liang, Xuefei
;
Zeng, Jing
;
Ding, Nan
;
Liang, Zhongzhen
;
Jian, Qiliang
;
Du, Hong
;
Liu, Junxi
;
Wang, Fang
Favorite
  |  
  
Submit date:2019/11/03
Isocorydine
cell cycle arrest
epithelial mesenchymal transition
mesenchymal-epithelial transition
antitumor
SiHa cells
异紫堇碱及其类似物的抗癌活性研究
会议论文
第21届全国色谱学术报告会及仪器展览会, 中国甘肃兰州
Authors:
闫倩,
;
李如霞,
;
辛爱一,
;
柳军玺
;
韩寅
;
李文广
;
邸多隆
Favorite
  |  
  
Submit date:2023/11/27
阿朴啡类生物碱
抗癌活性
构效关系
异紫堇碱
异紫堇碱及其类似物的抗癌活性研究
期刊论文
中国中药杂志, 2017, 卷号: 42, 期号: 16, 页码: 3152-3158
Authors:
闫倩
;
李如霞
;
辛爱一
;
柳军玺
;
李文广
;
邸多隆
Favorite
  |  
  
Submit date:2018/05/28
阿朴啡类生物碱
抗癌活性
构效关系
异紫堇碱
Total content determination for the effective fraction of the alkaloids in Dicranostigma leptopodum (Maxim.) Fedde by HPLC and ultraviolet-visible spectrophotometry
期刊论文
Analytical Methods, 2016, 卷号: 8, 期号: 12, 页码: 2645-2652
Authors:
Chen, Yali
;
Li, Ruxia
;
Gao, Rongrong
;
Yan, Qian
;
Zhong, Mei
;
Liu, Junxi
;
Zhao, QY(赵全义)
;
Di, Duolong
Favorite
  |  
  
Submit date:2017/01/11
Study on pharmacokinetics and tissue distribution of the isocorydine derivative (AICD) in rats by HPLC-DAD method
期刊论文
Acta Pharmaceutica Sinica B, 2015, 卷号: 5, 期号: 3, 页码: 238-245
Authors:
Chen Yali
;
Yan Qian
;
Zhong Mei
;
Zhao Quanyi
;
Liu Junxi
;
Di Duolong
;
Liu Jinxia
Favorite
  |  
  
Submit date:2017/04/05
Alkaloids
Pharmacokinetics
Tissue distribution
High-performance liquid chromatography with diode-array detection
8-Acetamino-isocorydine
高新技术开发区综合服务体系构建研究——以兰州高新区彭家坪新区为例
科技成果
2014
Authors:
姚远
;
吴建祖
;
白建民
;
雷亮
;
刘红芹
;
焦静茹
;
刘小峒
;
陈俊喜
Favorite
  |  
  
Submit date:2023/11/24
高新技术
高新区
综合服务体系
公共服务平台
异紫堇二酮体内外抗肿瘤活性研究
期刊论文
中国药理学通报, 2013, 卷号: 29, 期号: 6, 页码: 832-836
Authors:
卜令娜
;
赵剑喜
;
李文广
;
柳军玺
;
刘晔玮
Favorite
  |  
  
Submit date:2016/09/05
抗肿瘤
异紫堇二酮
生物碱
活性评价
细胞周期
诱导凋亡