兰州大学机构库

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Design and synthesis of novel PEG-conjugated 20(S)-camptothecin sulfonylamidine derivatives with potent in vitro antitumor activity via Cu-catalyzed three-component reaction 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 13, 页码: 2690-2693
Authors:  Song, ZL;  Chen, HL;  Wang, YH;  Goto, M;  Gao, WJ;  Cheng, PL;  Morris-Natschke, SL;  Liu, YQ;  Zhu, GX;  Wang, MJ...Song, ZL;  Chen, HL;  Wang, YH;  Goto, M;  Gao, WJ;  Cheng, PL;  Morris-Natschke, SL;  Liu, YQ;  Zhu, GX;  Wang, MJ;  Lee, KH;  Liu, YQ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
Favorite  |    Submit date:2017/01/11
Camptothecin  C-20 position  Cytotoxic activity  Poly(ethylene glycol) (PEG)  Sulfonylamidine  
Design, synthesis, and cytotoxic activity of novel 7-substituted camptothecin derivatives incorporating piperazinyl-sulfonylamidine moieties 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 9, 页码: 3959-3962
Authors:  Yang, CJ;  Song, ZL;  Goto, M;  Liu, YQ;  Hsieh, KY;  Morris-Natschke, SL;  Zhao, YL;  Zhang, JX;  Lee, KH;  Lee, KH (reprint author), Univ N Carolina, UNC Eshelman Sch Pharm, Nat Prod Res Labs, Chapel Hill, NC 27599 USA....Yang, CJ;  Song, ZL;  Goto, M;  Liu, YQ;  Hsieh, KY;  Morris-Natschke, SL;  Zhao, YL;  Zhang, JX;  Lee, KH;  Lee, KH (reprint author), Univ N Carolina, UNC Eshelman Sch Pharm, Nat Prod Res Labs, Chapel Hill, NC 27599 USA.
Favorite  |    Submit date:2018/09/28
Camptothecin  Cytotoxic activity  Piperazine  Sulfonylamidine  Synthesis  
Design and one-pot synthesis of new 7-acyl camptothecin derivatives as potent cytotoxic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 24, 页码: 7659-7661
Authors:  Liu, YQ(刘映前);  Dai, W;  Wang, CY;  Morris-Natschke, SL;  Zhou, XW;  Yang, L;  Yang, XM;  Li, WQ;  Lee, KH;  Liu, YQ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China....Liu, YQ(刘映前);  Dai, W;  Wang, CY;  Morris-Natschke, SL;  Zhou, XW;  Yang, L;  Yang, XM;  Li, WQ;  Lee, KH;  Liu, YQ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
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Camptothecin  Synthesis  Cytotoxic activity  
Design, semisynthesis and potent cytotoxic activity of novel 10-fluorocamptothecin derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 20, 页码: 4694-4697
Authors:  Yang, CJ;  Song, ZL;  Goto, M;  Hsu, PL;  Zhang, XS;  Yang, QR;  Liu, YQ;  Wang, MJ;  Morris-Natschke, SL;  Shang, XF...Yang, CJ;  Song, ZL;  Goto, M;  Hsu, PL;  Zhang, XS;  Yang, QR;  Liu, YQ;  Wang, MJ;  Morris-Natschke, SL;  Shang, XF;  Lee, KH;  Liu, YQ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Gansu, Peoples R China.;  Lee, KH (reprint author), Univ N Carolina, UNC Eshelman Sch Pharm, Nat Prod Res Labs, Chapel Hill, NC 27599 USA.
Favorite  |    Submit date:2018/09/28
Camptothecin  Cytotoxic activity  Fluorination  Synthesis  
Design, synthesis and potent cytotoxic activity of novel podophyllotoxin derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 8, 页码: 2363-2369
Authors:  Li, WQ;  Wang, XL;  Qian, KD;  Liu, YQ(刘映前);  Wang, CY;  Yang, L;  Tian, J;  Morris-Natschke, SL;  Zhou, XW;  Lee, KH...Li, WQ;  Wang, XL;  Qian, KD;  Liu, YQ(刘映前);  Wang, CY;  Yang, L;  Tian, J;  Morris-Natschke, SL;  Zhou, XW;  Lee, KH;  Liu, YQ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
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Podophyllotoxin  Acyl thiourea  Synthesis  Cytotoxic activity  
Synthesis of novel spin-labeled derivatives of 5-FU as potential antineoplastic agents 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: 7, 页码: 3269-3273
Authors:  Yang, L;  Wang, MJ;  Zhang, ZJ;  Morris-Natschke, SL;  Goto, M;  Tian, J;  Liu, YQ(刘映前);  Wang, CY;  Tian, X;  Yang, XM...Yang, L;  Wang, MJ;  Zhang, ZJ;  Morris-Natschke, SL;  Goto, M;  Tian, J;  Liu, YQ(刘映前);  Wang, CY;  Tian, X;  Yang, XM;  Lee, KH;  Liu, YQ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
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5-Fluorouracil  Spin-labeled  Nitroxide  Cytotoxicity  
Design, synthesis and cytotoxic activity of novel sulfonylurea derivatives of podophyllotoxin 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 1, 页码: 204-210
Authors:  Zhang, ZJ;  Tian, J;  Wang, LT;  Wang, MJ;  Nan, X;  Yang, L;  Liu, YQ(刘映前);  Morris-Natschke, SL;  Lee, KH;  Liu, YQ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China....Zhang, ZJ;  Tian, J;  Wang, LT;  Wang, MJ;  Nan, X;  Yang, L;  Liu, YQ(刘映前);  Morris-Natschke, SL;  Lee, KH;  Liu, YQ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
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Podophyllotoxin  Sulfonylurea  Synthesis  Cytotoxic activity  
Synthesis and mechanistic studies of novel spin-labeled combretastatin derivatives as potential antineoplastic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 5, 页码: 1248-1256
Authors:  Liu, YQ(刘映前);  Li, XJ;  Zhao, CY(赵春燕);  Nan, X;  Tian, J;  Morris-Natschke, SL;  Zhang, ZJ;  Yang, XM;  Yang, L;  Li, LH...Liu, YQ(刘映前);  Li, XJ;  Zhao, CY(赵春燕);  Nan, X;  Tian, J;  Morris-Natschke, SL;  Zhang, ZJ;  Yang, XM;  Yang, L;  Li, LH;  Zhou, XW;  Lee, KH;  Liu, YQ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
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Combretastatin  Spin-labeled  Nitroxide  Cytotoxicity  Mechanistic analysis  
Design, synthesis, crystal structure, bioactivity, and molecular docking studies of novel sulfonylamidine-derived neonicotinoid analogs 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: 12, 页码: 5043-5057
Authors:  Yang, L;  Zhao, YL;  Zhao, CY(赵春燕);  Li, HH;  Wang, MJ;  Morris-Natschke, SL;  Qian, KD;  Lee, KH;  Liu, YQ(刘映前);  Liu, YQ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China....Yang, L;  Zhao, YL;  Zhao, CY(赵春燕);  Li, HH;  Wang, MJ;  Morris-Natschke, SL;  Qian, KD;  Lee, KH;  Liu, YQ(刘映前);  Liu, YQ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
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Sulfonylamidine  Acaricidal activity  Insecticidal activity  X-ray diffraction  Molecular docking