兰州大学机构库

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VF-13, a chimeric peptide of VD-hemopressin(alpha) and neuropeptide VF, produces potent antinociception with reduced cannabinoid-related side effects 期刊论文
NEUROPHARMACOLOGY, 2020, 卷号: 175
Authors:  Xu, B(许彪);  Xiao, Jian;  Xu, Kangtai;  Zhang, Qinqin;  Chen, Dan;  Zhang, Run;  Zhang, Mengna;  Zhu, Hanwen;  Niu, Jiandong;  Zheng, Ting...Xu, B(许彪);  Xiao, Jian;  Xu, Kangtai;  Zhang, Qinqin;  Chen, Dan;  Zhang, Run;  Zhang, Mengna;  Zhu, Hanwen;  Niu, Jiandong;  Zheng, Ting;  Li, N(李宁);  Zhang, XY(张小郁);  Fang, Q(方泉)
Favorite  |    Submit date:2020/12/18
Cannabinoid  Neuropeptide FF  Chimeric peptide  Analgesia  Non-tolerance  
NOP01, a NOP receptor agonist, produced potent and peripherally restricted antinociception in a formalin-induced mouse orofacial pain model 期刊论文
NEUROPEPTIDES, 2022, 卷号: 91
Authors:  Xiao, Jian;  Niu, Jiandong;  Xu, B(许彪);  Zhang, Run;  Zhang, Mengna;  Zhang, N(张楠);  Xu, Kangtai;  Zhang, Qinqin;  Chen, Dan;  Shi, Yonghang...Xiao, Jian;  Niu, Jiandong;  Xu, B(许彪);  Zhang, Run;  Zhang, Mengna;  Zhang, N(张楠);  Xu, Kangtai;  Zhang, Qinqin;  Chen, Dan;  Shi, Yonghang;  Fang, Q(方泉);  Li, N(李宁)
Favorite  |    Submit date:2022/07/01
NOP01  Orofacial pain  NOP receptor  Peripheral antinociception  
Spinal DN-9, a Peptidic Multifunctional Opioid/Neuropeptide FF Agonist Produced Potent Nontolerance Forming Analgesia With Limited Side Effects 期刊论文
JOURNAL OF PAIN, 2020, 卷号: 21, 期号: 3-4, 页码: 477-493
Authors:  Wang, Zilong;  Xu, B(许彪);  Jiang, Changyu;  Zhang, Ting;  Zhang, Mengna;  Li, N(李宁);  Zhang, Qinqin;  Xu, Kangtai;  Chen, Dan;  Xiao, Jian...Wang, Zilong;  Xu, B(许彪);  Jiang, Changyu;  Zhang, Ting;  Zhang, Mengna;  Li, N(李宁);  Zhang, Qinqin;  Xu, Kangtai;  Chen, Dan;  Xiao, Jian;  Fang, Q(方泉)
Favorite  |    Submit date:2020/12/18
Analgesic  neuropeptide FF (NPFF)  opioid  pain  analgesic tolerance  opioid dependence  
Spinal endomorphins attenuate burn-injury pain in male mice by inhibiting p38 MAPK signaling pathway through the mu-opioid receptor 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 903
Authors:  Zhang, Ting;  Zhang, Run;  Xu, B(许彪);  Zhang, Mengna;  Zhang, Qinqin;  Li, N(李宁);  Qiu, Yu;  Chen, Dan;  Xu, Kangtai;  Xiao, Jian...Zhang, Ting;  Zhang, Run;  Xu, B(许彪);  Zhang, Mengna;  Zhang, Qinqin;  Li, N(李宁);  Qiu, Yu;  Chen, Dan;  Xu, Kangtai;  Xiao, Jian;  Zhang, N(张楠);  Fang, Q(方泉)
Favorite  |    Submit date:2021/08/12
Endomorphins  Mu-opioid receptor  Burn injury-induced pain  p38 MAPK  ERK1  2  
CB1 cannabinoid receptor agonist mouse VD-hemopressin(alpha) produced supraspinal analgesic activity in the preclinical models of pain 期刊论文
BRAIN RESEARCH, 2018, 卷号: 1680, 页码: 155-164
Authors:  Zheng, Ting;  Zhang, Run;  Zhang, Ting;  Zhang, Meng-Na;  Xu, B(许彪);  Song, JJ(宋竟婧);  Li, N(李宁);  Tang, Hong-Hai;  Wang, Pei;  Wang, R(王锐)...Zheng, Ting;  Zhang, Run;  Zhang, Ting;  Zhang, Meng-Na;  Xu, B(许彪);  Song, JJ(宋竟婧);  Li, N(李宁);  Tang, Hong-Hai;  Wang, Pei;  Wang, R(王锐);  Fang, Q(方泉)
Favorite  |    Submit date:2018/09/28
Cannabinoids  VD-hemopressin(alpha)  Antinociception  Post-operative pain  Formalin pain  Visceral pain  
Preemptive intrathecal administration of endomorphins relieves inflammatory pain in male mice via inhibition of p38 MAPK signaling and regulation of inflammatory cytokines 期刊论文
Journal of Neuroinflammation, 2018, 卷号: 15
Authors:  Zhang, Ting;  Zhang, N(张楠);  Zhang, Run;  Zhao, Weidong;  Chen, Yong;  Wang, Zilong;  Xu, B(许彪);  Zhang, Mengna;  Shi, XR(石学睿);  Zhang, Qinqin...Zhang, Ting;  Zhang, N(张楠);  Zhang, Run;  Zhao, Weidong;  Chen, Yong;  Wang, Zilong;  Xu, B(许彪);  Zhang, Mengna;  Shi, XR(石学睿);  Zhang, Qinqin;  Guo, Yuanyuan;  Xiao, Jian;  Chen, Dan;  Fang, Q(方泉)
Favorite  |    Submit date:2019/10/28
Endomorphin  Preemptive analgesic  Inflammatory pain  p38 MAPK  Inflammatory cytokines  
Structure-Activity Relationships of a Novel Cyclic Hexapeptide That Exhibits Multifunctional Opioid Agonism and Produces Potent Antinociceptive Activity 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 67, 期号: 1, 页码: 272-288
Authors:  Zhang, Qinqin;  Xu, B(许彪);  Chen, Dan;  Wu, Shuyuan;  Hu, Xuanran;  Zhang, Xiaodi;  Yu, Bowen;  Zhang, Shichao;  Yang, Zhenyun;  Zhang, Mengna...Zhang, Qinqin;  Xu, B(许彪);  Chen, Dan;  Wu, Shuyuan;  Hu, Xuanran;  Zhang, Xiaodi;  Yu, Bowen;  Zhang, Shichao;  Yang, Zhenyun;  Zhang, Mengna;  Fang, Q(方泉)
Favorite  |    Submit date:2024/03/15
The blockade of neuropeptide FF receptor 1 and 2 differentially contributed to the modulating effects on fentanyl-induced analgesia and hyperalgesia in mice 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2024, 卷号: 969
Authors:  Chen, Dan;  Zhang, Mengna;  Zhang, Qinqin;  Wu, Shuyuan;  Yu, Bowen;  Zhang, Xiaodi;  Hu, Xuanran;  Zhang, Shichao;  Yang, Zhenyun;  Kuang, Junzhe...Chen, Dan;  Zhang, Mengna;  Zhang, Qinqin;  Wu, Shuyuan;  Yu, Bowen;  Zhang, Xiaodi;  Hu, Xuanran;  Zhang, Shichao;  Yang, Zhenyun;  Kuang, Junzhe;  Xu, B(许彪);  Fang, Q(方泉)
Favorite  |    Submit date:2024/05/24
Neuropeptide FF  Neuropeptide FF receptor 1  Neuropeptide FF receptor 2  Fentanyl  Analgesia  Hyperalgesia  
A Novel Multi-Target Mu/Delta Opioid Receptor Agonist, HAGD, Produced Potent Peripheral Antinociception with Limited Side Effects in Mice and Minimal Impact on Human Sperm Motility In Vitro 期刊论文
MOLECULES, 2023, 卷号: 28, 期号: 1
Authors:  Li, Fangfang;  Yue, Feng;  Zhang, Wei;  Xu, B(许彪);  Wang, Yiqing;  Zhang, Xuehong
Adobe PDF(2209Kb)  |  Favorite  |    Submit date:2023/02/22
pain  analgesic  opioid  infertility  sperm motility  
Discovery of two novel branched peptidomimetics containing endomorphin-2 and RF9 pharmacophores: Synthesis and neuropharmacological evaluation 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 4, 页码: 630-643
Authors:  Zhang, Ting;  Han, Zhenglan;  Shi, XR(石学睿);  Zhao, Weidong;  Wang, Zilong;  Zhang, Run;  Xu, B(许彪);  Zhang, Mengna;  Zhang, Qinqin;  Xiao, Jian...Zhang, Ting;  Han, Zhenglan;  Shi, XR(石学睿);  Zhao, Weidong;  Wang, Zilong;  Zhang, Run;  Xu, B(许彪);  Zhang, Mengna;  Zhang, Qinqin;  Xiao, Jian;  Zhu, Hanwen;  Zheng, Ting;  Fang, Q(方泉)
Favorite  |    Submit date:2019/10/24
Branched peptidomimetics  Endomorphin-2  RF9  Antinociception  Tolerance  Constipation