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Short, mirror-symmetric antimicrobial peptides centered on ?RRR? have broad-spectrum antibacterial activity with low drug resistance and toxicity
期刊论文
ACTA BIOMATERIALIA, 2022, 卷号: 154, 页码: 145-167
Authors:
Zhang, Fangyan
;
Yang, Ping
;
Mao, Wenbo
;
Zhong, Chao
;
Zhang, Jingying
;
Chang, Linlin
;
Wu, Xiaoyan
;
Liu, H(刘晖)
;
Zhang, Y(张云)
;
Gou, Sanhu
...
Zhang, Fangyan
;
Yang, Ping
;
Mao, Wenbo
;
Zhong, Chao
;
Zhang, Jingying
;
Chang, Linlin
;
Wu, Xiaoyan
;
Liu, H(刘晖)
;
Zhang, Y(张云)
;
Gou, Sanhu
;
Ni, JM(倪京满)
Favorite
  |  
  
Submit date:2023/02/22
Antimicrobial peptides
Mirror -symmetric structure
Bacterial resistance
Multiple mechanisms
In vitro and in vivo
Improving the Antimicrobial Performance of Amphiphilic Cationic Antimicrobial Peptides Using Glutamic Acid Full-Scan and Positive Charge Compensation Strategies
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2022
Authors:
Ouyang, Xu
;
Li, Beibei
;
Yang, Yinyin
;
Ba, Zufang
;
Zhang, Jingying
;
Zhang, Tianyue
;
Chang, Linlin
;
Zhang, Fangyan
;
Zhang, Yun
;
Liu, Hui
...
Ouyang, Xu
;
Li, Beibei
;
Yang, Yinyin
;
Ba, Zufang
;
Zhang, Jingying
;
Zhang, Tianyue
;
Chang, Linlin
;
Zhang, Fangyan
;
Zhang, Yun
;
Liu, Hui
;
Gou, Sanhu
;
Ni, Jingman
Favorite
  |  
  
Submit date:2022/11/09
Antimicrobial peptides–antibiotics combination: An effective strategy targeting drug-resistant Gram-negative bacteria
期刊论文
Peptide Science, 2022, 卷号: 114, 期号: 4
Authors:
Zhang, Fangyan
;
Zhong, Chao
;
Yao, Jia
;
Zhang, Jingying
;
Zhang, Tianyue
;
Li, Beibei
;
Gou, Sanhu
;
Ni, JM(倪京满)
Favorite
  |  
  
Submit date:2022/11/08
Chemical detection
Bacteria
Peptides
Anti-resistance mechanism
Antibiotic-resistant bacteria
Antimicrobial peptide
Antimicrobial resistances
Clinical application
Combination therapy
Gram-negative bacteria
Outer membrane permeability
Peptide antibiotics
Resistance mechanisms
Antimicrobial peptides–antibiotics combination: An effective strategy targeting drug-resistant Gram-negative bacteria
期刊论文
Peptide Science, 2022, 卷号: 114, 期号: 4
Authors:
Zhang, Fangyan
;
Zhong, Chao
;
Yao, Jia
;
Zhang, Jingying
;
Zhang, Tianyue
;
Li, Beibei
;
Gou, Sanhu
;
Ni, Jingman
Favorite
  |  
  
Submit date:2023/01/03
Chemical detection
Bacteria
Peptides
Anti-resistance mechanism
Antibiotic-resistant bacteria
Antimicrobial peptide
Antimicrobial resistances
Clinical application
Combination therapy
Gram-negative bacteria
Outer membrane permeability
Peptide antibiotics
Resistance mechanisms
Constructing new acid-activated anticancer peptide by attaching a desirable anionic binding partner peptide
期刊论文
JOURNAL OF DRUG TARGETING, 2022
Authors:
Zhang, Y(张云)
;
Chang, Linlin
;
Bao, Hexin
;
Wu, Xiaoyan
;
Liu, H(刘晖)
;
Gou, Sanhu
;
Zhang, Jingying
;
Ni, JM(倪京满)
Favorite
  |  
  
Submit date:2022/07/01
Anticancer peptide
anionic binding partner
acid activated
low toxicity
enzymatic stability
Novel beta-Hairpin Antimicrobial Peptides Containing the beta-Turn Sequence of -RRRF- Having High Cell Selectivity and Low Incidence of Drug Resistance br
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 7, 页码: 5625-5641
Authors:
Li, Beibei
;
Ouyang, Xu
;
Ba, Zufang
;
Yang, Yinyin
;
Zhang, Jingying
;
Liu, H(刘晖)
;
Zhang, Tianyue
;
Zhang, Fangyan
;
Zhang, Y(张云)
;
Gou, Sanhu
...
Li, Beibei
;
Ouyang, Xu
;
Ba, Zufang
;
Yang, Yinyin
;
Zhang, Jingying
;
Liu, H(刘晖)
;
Zhang, Tianyue
;
Zhang, Fangyan
;
Zhang, Y(张云)
;
Gou, Sanhu
;
Ni, JM(倪京满)
Favorite
  |  
  
Submit date:2022/07/01
Antimicrobial peptides-antibiotics combination: An effective strategy targeting drug-resistant Gram-negative bacteria
期刊论文
PEPTIDE SCIENCE, 2022
Authors:
Zhang, Fangyan
;
Zhong, Chao
;
Yao, Jia
;
Zhang, Jingying
;
Zhang, Tianyue
;
Li, Beibei
;
Gou, Sanhu
;
Ni, JM(倪京满)
Favorite
  |  
  
Submit date:2022/04/20
antimicrobial peptides
antimicrobial resistance
anti-resistance mechanisms
combination therapy
Gram-negative bacteria
Antibiotics
Chemical detection
Peptides
Anti-resistance mechanism
Antibiotic-resistant bacteria
Antimicrobial peptide
Antimicrobial resistances
Clinical application
Combination therapy
Outer membrane permeability
Peptide antibiotics
Resistance mechanisms
Short, mirror-symmetric antimicrobial peptides centered on "RRR" have broad-spectrum antibacterial activity with low drug resistance and toxicity
期刊论文
Acta Biomaterialia, 2022
Authors:
Zhang, Fangyan
;
Yang, Ping
;
Mao, Wenbo
;
Zhong, Chao
;
Zhang, Jingying
;
Chang, Linlin
;
Wu, Xiaoyan
;
Liu, Hui
;
Zhang, Yun
;
Gou, Sanhu
...
Zhang, Fangyan
;
Yang, Ping
;
Mao, Wenbo
;
Zhong, Chao
;
Zhang, Jingying
;
Chang, Linlin
;
Wu, Xiaoyan
;
Liu, Hui
;
Zhang, Yun
;
Gou, Sanhu
;
Ni, JM(倪京满)
Favorite
  |  
  
Submit date:2023/01/03
Antibiotics
Hydrophobicity
Microorganisms
Peptides
Toxicity
Anti
bacterial activity
Antimicrobial peptide
Bacterial resistance
In vitro and in vivo
In
vitro
Mirror
symmetric structure
Multiple mechanism
Symmetric structures
Symmetrics
Vitro and in vivo
Novel Broad-Spectrum Antimicrobial Peptide Derived from Anoplin and Its Activity on Bacterial Pneumonia in Mice
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 11247-11266
Authors:
Gou, Sanhu
;
Li, Beibei
;
Ouyang, Xu
;
Ba, Zufang
;
Zhong, Chao
;
Zhang, Tianyue
;
Chang, LinLin
;
Zhu, Yuewen
;
Zhang, Jingying
;
Zhu, Ningyi
...
Gou, Sanhu
;
Li, Beibei
;
Ouyang, Xu
;
Ba, Zufang
;
Zhong, Chao
;
Zhang, Tianyue
;
Chang, LinLin
;
Zhu, Yuewen
;
Zhang, Jingying
;
Zhu, Ningyi
;
Zhang, Y(张云)
;
Liu, H(刘晖)
;
Ni, JM(倪京满)
Favorite
  |  
  
Submit date:2021/12/15
New Antimicrobial Peptides with Repeating Unit against Multidrug-Resistant Bacteria
期刊论文
ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 6, 页码: 1619-1637
Authors:
Zhong, Chao
;
Zhang, Fangyan
;
Yao, Jia
;
Zhu, Yuewen
;
Zhu, Ningyi
;
Zhang, Jingying
;
Ouyang, Xu
;
Zhang, Tianyue
;
Li, Beibei
;
Xie, JQ(谢俊秋)
...
Zhong, Chao
;
Zhang, Fangyan
;
Yao, Jia
;
Zhu, Yuewen
;
Zhu, Ningyi
;
Zhang, Jingying
;
Ouyang, Xu
;
Zhang, Tianyue
;
Li, Beibei
;
Xie, JQ(谢俊秋)
;
Ni, JM(倪京满)
Favorite
  |  
  
Submit date:2021/08/12
antimicrobial peptides
repeating unit
antimicrobial activity
multidrug-resistant bacteria
anti-resistance
multiple mechanisms