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Novel Broad-Spectrum Antimicrobial Peptide Derived from Anoplin and Its Activity on Bacterial Pneumonia in Mice
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 11247-11266
Authors:
Gou, Sanhu
;
Li, Beibei
;
Ouyang, Xu
;
Ba, Zufang
;
Zhong, Chao
;
Zhang, Tianyue
;
Chang, LinLin
;
Zhu, Yuewen
;
Zhang, Jingying
;
Zhu, Ningyi
...
Gou, Sanhu
;
Li, Beibei
;
Ouyang, Xu
;
Ba, Zufang
;
Zhong, Chao
;
Zhang, Tianyue
;
Chang, LinLin
;
Zhu, Yuewen
;
Zhang, Jingying
;
Zhu, Ningyi
;
Zhang, Yun
;
Liu, Hui
;
Ni, Jingman
Favorite
  |  
  
Submit date:2021/12/15
New Antimicrobial Peptides with Repeating Unit against Multidrug-Resistant Bacteria
期刊论文
ACS Infectious Diseases, 2021, 卷号: 7, 期号: 6, 页码: 1619-1637
Authors:
Zhong, Chao
;
Zhang, Fangyan
;
Yao, Jia
;
Zhu, Yuewen
;
Zhu, Ningyi
;
Zhang, Jingying
;
Ouyang, Xu
;
Zhang, Tianyue
;
Li, Beibei
;
Xie, Junqiu
...
Zhong, Chao
;
Zhang, Fangyan
;
Yao, Jia
;
Zhu, Yuewen
;
Zhu, Ningyi
;
Zhang, Jingying
;
Ouyang, Xu
;
Zhang, Tianyue
;
Li, Beibei
;
Xie, Junqiu
;
Ni, Jingman
Favorite
  |  
  
Submit date:2021/08/12
antimicrobial peptides
repeating unit
antimicrobial activity
multidrug-resistant bacteria
anti-resistance
multiple mechanisms
抗菌肽Mastoparan-C新型类似物的设计、合成、构效关系及其抑制和逆转抗生素耐药性作用研究
学位论文
医学硕士, 兰州: 兰州大学, 2021
Authors:
朱宁艺
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  |  
  
Submit date:2021/12/06
抗菌肽
Mastoparan-C
抗菌活性
细胞毒性
抗生素耐药性
抗生素佐剂
Antimicrobial peptides with symmetric structures against multidrug-resistant bacteria while alleviating antimicrobial resistance
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 186
Authors:
Zhong, Chao
;
Zhang, Fangyan
;
Yao, Jia
;
Zhu, Yuewen
;
Zhu, Ningyi
;
Zhang, Yun
;
Liu, Hui
;
Gou, Sanhu
;
Ni, Jingman
Favorite
  |  
  
Submit date:2021/06/17
Antimicrobial peptidesAntimicrobial activityAnti-resistanceMultidrug-resistant bacteriaBiocompatibilityMultiple mechanisms
Newly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 卷号: 158
Authors:
Zhu, Ningyi
;
Zhong, Chao
;
Liu, Tianqi
;
Zhu, Yuewen
;
Gou, Sanhu
;
Bao, Hexin
;
Yao, Jia
;
Ni, Jingman
Favorite
  |  
  
Submit date:2021/04/16
Antimicrobial peptides
Cell selectivity
Antibiotic adjuvant
Rifampin
Rifampin-resistant Escherichia coli
Gram-negative bacteria
Ultra-short lipopeptides against gram-positive bacteria while alleviating antimicrobial resistance
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 212
Authors:
Zhong, Chao
;
Zhang, Fangyan
;
Zhu, Ningyi
;
Zhu, Yuewen
;
Yao, Jia
;
Gou, Sanhu
;
Xie, Junqiu
;
Ni, Jingman
Favorite
  |  
  
Submit date:2021/06/17
Ultra-short lipopeptidesGram-positive bacteriaAntimicrobial activityCell selectivityAnti-resistance
Effect of N-methylated and fatty acid conjugation on analogs of antimicrobial peptide Anoplin
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020, 卷号: 152
Authors:
Liu, Tianqi
;
Zhu, Ningyi
;
Zhong, Chao
;
Zhu, Yuewen
;
Gou, Sanhu
;
Chang, Linlin
;
Bao, Hexin
;
Liu, Hui
;
Zhang, Yun
;
Ni, Jingman
...
Liu, Tianqi
;
Zhu, Ningyi
;
Zhong, Chao
;
Zhu, Yuewen
;
Gou, Sanhu
;
Chang, Linlin
;
Bao, Hexin
;
Liu, Hui
;
Zhang, Yun
;
Ni, Jingman
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  |  
  
Submit date:2020/12/20
Antimicrobial peptides
Anoplin
N-methyl amino acid
Fatty acid conjugation
Proteolytic stability
Synthesis and anti-pseudomonal activity of new beta-Ala modified analogues of the antimicrobial peptide anoplin
期刊论文
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2020, 卷号: 310, 期号: 5
Authors:
Zhong, Chao
;
Zhu, Yuewen
;
Zhu, Ningyi
;
Liu, Tianqi
;
Gou, Sanhu
;
Zhang, Fangyan
;
Yao, JIa
;
Xie, Junqiu
;
Ni, Jingman
Favorite
  |  
  
Submit date:2020/12/20
beta-Ala
Antimicrobial peptides
Pseudomonas aeruginosa
Multidrug-resistant strains
Biological activitiy
Study on the effects of different dimerization positions on biological activity of partial D-Amino acid substitution analogues of Anoplin
期刊论文
MICROBIAL PATHOGENESIS, 2020, 卷号: 139
Authors:
Zhong, Chao
;
Gou, Sanhu
;
Liu, Tianqi
;
Zhu, Yuewen
;
Zhu, Ningyi
;
Liu, Hui
;
Zhang, Yun
;
Xie, Junqiu
;
Guo, Xiaomin
;
Ni, Jingman
...
Zhong, Chao
;
Gou, Sanhu
;
Liu, Tianqi
;
Zhu, Yuewen
;
Zhu, Ningyi
;
Liu, Hui
;
Zhang, Yun
;
Xie, Junqiu
;
Guo, Xiaomin
;
Ni, Jingman
Adobe PDF(9995Kb)
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  |  
  
Submit date:2020/08/27
Multidrug-resistant bacteria
Anoplin
Dimer antimicrobial peptides
Different dimerization positions
Biological activity
Antimicrobial peptides conjugated with fatty acids on the side chain of D-amino acid promises antimicrobial potency against multidrug-resistant bacteria
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020, 卷号: 141
Authors:
Zhong, Chao
;
Zhu, Ningyi
;
Zhu, Yuewen
;
Liu, Tianqi
;
Gou, Sanhu
;
Xie, Junqiu
;
Yao, Jia
;
Ni, Jingman
Favorite
  |  
  
Submit date:2020/08/27
Antimicrobial peptides
Anoplin
Fatty acids conjugation
Side chain
D-amino acid
Hydrophobicity
Antimicrobial activity