兰州大学机构库

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基于IL-6R运用分子对接筛选红芪防护BMSCs的活性成分 期刊论文
重庆医科大学学报, 2019, 卷号: 44, 期号: 7, 页码: 867-871
Authors:  冯彩琴;  骆亚莉;  刘永琦;  靳晓杰;  石丹枫;  朱永昌;  刘东玲;  李玲;  李研
Favorite  |    Submit date:2020/08/04
白介素-6受体  红芪  骨髓间充质干细胞  分子对接  
基于分子对接探讨红芪中小分子拮抗肿瘤坏死因子受体1的可能性 期刊论文
中国实验方剂学杂志, 2019, 卷号: 25, 期号: 17, 页码: 173-180
Authors:  李研;  骆亚莉;  刘永琦;  冯彩琴;  靳晓杰;  朱永昌
Favorite  |    Submit date:2020/07/21
红芪  分子对接  肿瘤坏死因子受体1拮抗剂(TNFR1)  
靶向STING蛋白激动剂的筛选和活性评价及蛋白构象转换机制研究 学位论文
理学博士, 兰州: 兰州大学, 2022
Authors:  朱永昌
Favorite  |    Submit date:2023/03/13
虚拟筛选  激动剂  构象转变  分子动力学模拟  
碳纳米颗粒和小分子影响朊蛋白聚集的机制研究 学位论文
硕士, 兰州: 兰州大学, 2018
Authors:  朱永昌
Favorite  |    Submit date:2019/01/18
碳纳米管  石墨烯  朊蛋白  聚集  分子动力学模拟  
乳腺肿块放射性核素显像与X线钼靶的对比研究 期刊论文
中华核医学杂志, 1999, 期号: 4, 页码: 1-1
Authors:  朱汇庆;  林祥通;  宋少莉;  任长才;  刘永昌;  何婉婷
Favorite  |    Submit date:2016/09/09
放射性核素显像  X线钼靶  显像剂  放射性浓聚  放射性异常浓聚  全身骨扫描  放化纯  腋窝淋巴结  腋下淋巴结  原位导管癌  
International expert consensus on diagnosis and treatment of lung cancer complicated by chronic obstructive pulmonary disease 期刊论文
Translational Lung Cancer Research, 2023, 卷号: 12, 期号: 8, 页码: 1661-1701
Authors:  Zhou, Chengzhi;  Qin, Yinyin;  Zhao, Wei;  Liang, Zhenyu;  Li, Min;  Liu, Dan;  Bai, Li;  Chen, Yahong;  Chen, Yan;  Cheng, Yuan...Zhou, Chengzhi;  Qin, Yinyin;  Zhao, Wei;  Liang, Zhenyu;  Li, Min;  Liu, Dan;  Bai, Li;  Chen, Yahong;  Chen, Yan;  Cheng, Yuan;  Chu, Tianqing;  Chu, Qian;  Deng, Haiyi;  Dong, Yuchao;  Fang, Wenfeng;  Fu, Xiuhua;  Gao, Beili;  Han, Yiping;  He, Yong;  Hong, Qunying;  Hu, Jie;  Hu, Yi;  Jiang, Liyan;  Jin, Yang;  Lan, Fen;  Li, Qiang;  Li, Shuben;  Li, Wen;  Li, Yaqing;  Liang, Wenhua;  Lin, Gen;  Lin, Xinqing;  Liu, Ming;  Liu, Xiaofang;  Liu, XJ(刘晓菊);  Liu, Zhefeng;  Lv, Tangfeng;  Mu, Chuanyong;  Ouyang, Ming;  Qin, Jianwen;  Ren, Shengxiang;  Shi, Huanzhong;  Shi, Minhua;  Su, Chunxia;  Su, Jin;  Sun, Dejun;  Sun, Yongchang;  Tang, Huaping;  Wang, Huijuan;  Wang, Kai;  Wang, Ke;  Wang, Mengzhao;  Wang, Qi;  Wang, Wei;  Wang, Xiaoping;  Wang, Yuehong;  Wang, Zhijie;  Wang, Zirui;  Wu, Lin;  Wu, Di;  Xie, Baosong;  Xie, Min;  Xie, Xiaohong;  Xie, Zhanhong;  Xu, Shufeng;  Xu, Xiaoman;  Yang, Xia;  Yin, Yan;  Yu, Zongyang;  Zhang, Jian;  Zhang, Jianqing;  Zhang, Jing;  Zhang, Xiaoju;  Zhang, Yingying;  Zhong, Diansheng;  Zhou, Qing;  Zhou, Xiangdong;  Zhou, Yanbin;  Zhu, Bo;  Zhu, Zhengfei;  Zou, Chenxi;  Zhong, Nanshan;  He, Jianxing;  Bai, Chunxue;  Hu, Chengping;  Li, Weimin;  Song, Yong;  Zhou, Jianying;  Han, Baohui;  Varga, Janos;  Barreiro, Esther;  Park, Hye Yun;  Petrella, Francesco;  Saito, Yuichi;  Goto, Taichiro;  Igai, Hitoshi;  Bravaccini, Sara;  Zanoni, Michele;  Solli, Piergiorgio;  Watanabe, Satoshi;  Fiorelli, Alfonso;  Nakada, Takeo;  Ichiki, Yoshinobu;  Berardi, Rossana;  Tsoukalas, Nikolaos;  Girard, Nicolas;  Rossi, Antonio;  Passaro, Antonio;  Hida, Toyoaki;  Li, Shiyue;  Chen, Liang'an;  Chen, Rongchang
Favorite  |    Submit date:2023/11/28
Lung cancer  chronic obstructive pulmonary disease (COPD)  concurrent treatment  
Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography 期刊论文
Computational and Structural Biotechnology Journal, 2021, 卷号: 19, 页码: 4079-4091
Authors:  Han, Jian-Ting;  Zhu, Yongchang;  Pan, Da-Bo;  Xue, Hong-Xiang;  Wang, Shuang;  Peng, Yali;  Liu, HX(刘焕香);  He, Yong-Xing;  Yao, XJ(姚小军)
Favorite  |    Submit date:2021/12/14
Conformations  Diseasecontrol  Hydrogenbonds  Hydrophobicity  Machinery  Neurodegenerativediseases  Peptides  Xraycrystallography  Bindingpockets  Computationalmodel  Dynamicssimulation  Humandisease  Interactionmodes  Neurodegeneration  Pentapeptides  Peptideinhibitors  Peptide  inhibitorhit  Structurebaseddrugdesigns  
Carbon Nanoparticles Inhibit the Aggregation of Prion Protein as Revealed by Experiments and Atomistic Simulations 期刊论文
Journal of Chemical Information and Modeling, 2019, 卷号: 59, 期号: 5, 页码: 1909-1918
Authors:  Zhou, Shuangyan;  Zhu, Yongchang;  Yao, Xiaojun;  Liu, Huanxiang
Favorite  |    Submit date:2019/10/14
Discovery of a new inhibitor targeting PD-L1 for cancer immunotherapy 期刊论文
NEOPLASIA, 2021, 卷号: 23, 期号: 3, 页码: 281-293
Authors:  Wang, Fengling;  Ye, Wenling;  Wang, Shuang;  He, Yongxing;  Zhong, Haiyang;  Wang, Yuwei;  Zhu, Yongchang;  Han, Jianting;  Bing, Zhitong;  Ji, Shaoping...Wang, Fengling;  Ye, Wenling;  Wang, Shuang;  He, Yongxing;  Zhong, Haiyang;  Wang, Yuwei;  Zhu, Yongchang;  Han, Jianting;  Bing, Zhitong;  Ji, Shaoping;  Liu, Huanxiang;  Yao, Xiaojun
Favorite  |    Submit date:2021/04/16
PD-1  PD-L1  Inhibitor  APBC  Cancer immunotherapy  
Discovery of novel and potent InhA direct inhibitors by ensemble docking-based virtual screening and biological assays 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2023, 卷号: 37, 期号: 12, 页码: 695-706
Authors:  Zhang, Qianqian;  Han, Jianting;  Zhu, Yongchang;  Yu, Fansen;  Hu, Xiaopeng;  Tong, Henry H. Y.;  Liu, Huanxiang
Favorite  |    Submit date:2023/11/28
MDR-TB  InhA direct inhibitors  Ensemble docking-based virtual screening  Biological assays  MD simulation  MM-GBSA calculation  Binding mode analysis