兰州大学机构库

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Cellulose filter paper immobilized α-glucosidase as a target enzyme-oriented fishing tool for screening inhibitors from Cyclocarya paliurus leaves 期刊论文
Arabian Journal of Chemistry, 2023, 卷号: 16, 期号: 6
Authors:  Li, Yan-Jun;  Wan, Guang-Zhen;  Guo, Zhao-Hui;  Chen, J(陈娟)
Favorite  |    Submit date:2023/07/18
Cellulose  Deposition  Hydrogen bonds  Liquid chromatography  Mass spectrometry  Molecular modeling  Plants (botany)  Van der Waals forces  Cellulose filters  Cyclocarya paliurus  Filter papers  Glucosidase  Glucosidase inhibitors  Molecular docking  Target enzyme-oriented fishing tool  UPLC Q-TOF MS  UPLC-QTOF-MS/MS  Α-glucosidase inhibitor  
Platanosides from Platanus x acerifolia: New molecules, SAR, and target validation of a strong lead for drug-resistant bacterial infections and the associated sepsis 期刊论文
BIOORGANIC CHEMISTRY, 2024, 卷号: 143
Authors:  Wu, Xi-Ying;  Zhao, Ze-Yu;  Osman, Ezzat E. A.;  Wang, XJ(王晓娟);  Choo, Yeun-Mun;  Benjamin, Menny M.;  Xiong, Juan;  Hamann, Mark T.;  Luo, Cheng;  Hu, Jin-Feng...Wu, Xi-Ying;  Zhao, Ze-Yu;  Osman, Ezzat E. A.;  Wang, XJ(王晓娟);  Choo, Yeun-Mun;  Benjamin, Menny M.;  Xiong, Juan;  Hamann, Mark T.;  Luo, Cheng;  Hu, Jin-Feng
Favorite  |    Submit date:2024/03/15
Platanus x acerifolia  Platanosides  Molecular ion networking (MoIN)  Antibacterial  Staphylococcus aureus  Enterococcus faecium  Structure -activity relationship (SAR)  Molecular docking  Target validation  
KDM6A suppresses hepatocellular carcinoma cell proliferation by negatively regulating the TGF-beta/SMAD signaling pathway 期刊论文
Experimental and Therapeutic Medicine, 2020, 卷号: 20, 期号: 3, 页码: 2774-2782
Authors:  Li, Yuan;  Yang, Jing;  Zhang, Xin;  Liu, Hong;  Guo, Jin
Favorite  |    Submit date:2020/12/18
lysine demethylase 6A  proliferation  molecular target  hepatocellular carcinoma  transforming growth factor-beta  SMAD  
Loss of post-translational modification sites in disease 会议论文
Pacific Symposium on Biocomputing 2010, PSB 2010, Kamuela, HI, United states, January 4, 2010 - January 8, 2010
Authors:  Li, Shuyan;  Iakoucheva, Lilia M.;  Mooney, Sean D.;  Radivojac, Predrag,;  Radivojac, P. (predrag@indiana.edu)
Favorite  |    Submit date:2017/01/20
Pathology  Amino acids  Amino acid substitution  Area of interest  Biology and medicine  Computational analysis  Human genetic disease  Molecular function  Physio-chemical properties  Post-translational modifications  Target sites  Wild types  
新白叶藤碱衍生物 Z24对灰葡萄孢菌的作用机制及靶标研究 学位论文
理学博士, 兰州: 兰州大学, 2023
Authors:  赵文斌
Favorite  |    Submit date:2023/11/15
新白叶藤碱衍生物Z24  neocryptolepine derivative Z24  灰葡萄孢菌  B. cinerea  分子靶标  molecular target  硫胺噻唑合酶  thiaminothiazole synthase  可变剪接  variable splicing  硫胺素代谢  thiamine metabolism  虚拟筛选  virtual screening  
Cellulose filter paper immobilized ?-glucosidase as a target enzyme-oriented fishing tool for screening inhibitors from Cyclocarya paliurus leaves 期刊论文
Arabian Journal of Chemistry, 2023, 卷号: 16, 期号: 6
Authors:  Li, Yan-Jun;  Wan, Guang-Zhen;  Guo, Zhao-Hui;  Chen, J(陈娟)
Favorite  |    Submit date:2023/05/25
Target enzyme-oriented fishing tool  a-Glucosidase inhibitors  Cyclocarya paliurus  UPLC-QTOF-MS  MS  Molecular docking  
Risk of serious adverse event and fatal adverse event with molecular target anticancer drugs in cancer patients: A meta-analysis 期刊论文
Journal of Cancer Research and Therapeutics, 2019, 卷号: 15, 期号: 7, 页码: 1435-1449
Authors:  Wang, Zhiwei;  Yang, Xiao;  Wang, Jitao;  Wang, Shuai;  Mao, Xiaorong;  Li, Mingxing;  Zhao, Yongzhao;  Wang, Weidong;  Qi, Xiaolong;  Wu, Tongwei...Wang, Zhiwei;  Yang, Xiao;  Wang, Jitao;  Wang, Shuai;  Mao, Xiaorong;  Li, Mingxing;  Zhao, Yongzhao;  Wang, Weidong;  Qi, Xiaolong;  Wu, Tongwei
Favorite  |    Submit date:2020/08/04
Cancer  fatal adverse event  molecular target anticancer therapy  serious adverse event  
What Contributes to Serotonin-Norepinephrine Reuptake Inhibitors' Dual-Targeting Mechanism? The Key Role of Transmembrane Domain 6 in Human Serotonin and Norepinephrine Transporters Revealed by Molecular Dynamics Simulation 期刊论文
ACS Chemical Neuroscience, 2018, 卷号: 9, 期号: 5, 页码: 1128-1140
Authors:  Xue, Weiwei;  Yang, Fengyuan;  Wang, Panpan;  Zheng, Guoxun;  Chen, Yuzong;  Yao, XJ(姚小军);  Zhu, Feng
Favorite  |    Submit date:2018/09/27
Serotonin-norepinephrine reuptake inhibitor  major depressive disorder  dual-target drug  binding mode  molecular dynamics