兰州大学机构库
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One New Acid-Activated Hybrid Anticancer Peptide by Coupling with a Desirable pH-Sensitive Anionic Partner Peptide 期刊论文
ACS Omega, 2023
Authors:  Chang, Linlin;  Wu, Xiaoyan;  Ran, Kaixin;  Tian, Yali;  Ouyang, Xu;  Liu, H(刘晖);  Gou, SH(缑三虎);  Zhang, Y(张云);  Ni, JM(倪京满)
Favorite  |    Submit date:2023/04/12
Constructing new acid-activated anticancer peptide by attaching a desirable anionic binding partner peptide 期刊论文
JOURNAL OF DRUG TARGETING, 2022, 卷号: 30, 期号: 9, 页码: 973-982
Authors:  Zhang, Y(张云);  Chang, Linlin;  Bao, Hexin;  Wu, Xiaoyan;  Liu, H(刘晖);  Gou, SH(缑三虎);  Zhang, Jingying;  Ni, JM(倪京满)
Favorite  |    Submit date:2022/07/01
Anticancer peptide  anionic binding partner  acid activated  low toxicity  enzymatic stability  
Novel beta-Hairpin Antimicrobial Peptides Containing the beta-Turn Sequence of -RRRF- Having High Cell Selectivity and Low Incidence of Drug Resistance br 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 7, 页码: 5625-5641
Authors:  Li, Beibei;  Ouyang, Xu;  Ba, Zufang;  Yang, Yinyin;  Zhang, Jingying;  Liu, H(刘晖);  Zhang, Tianyue;  Zhang, Fangyan;  Zhang, Y(张云);  Gou, SH(缑三虎)...Li, Beibei;  Ouyang, Xu;  Ba, Zufang;  Yang, Yinyin;  Zhang, Jingying;  Liu, H(刘晖);  Zhang, Tianyue;  Zhang, Fangyan;  Zhang, Y(张云);  Gou, SH(缑三虎);  Ni, JM(倪京满)
Favorite  |    Submit date:2022/07/01
Antimicrobial peptides with symmetric structures against multidrug-resistant bacteria while alleviating antimicrobial resistance 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 186
Authors:  Zhong, C(钟超);  Zhang, Fangyan;  Yao, Jia;  Zhu, Yuewen;  Zhu, Ningyi;  Zhang, Y(张云);  Liu, H(刘晖);  Gou, SH(缑三虎);  Ni, JM(倪京满)
Favorite  |    Submit date:2021/06/17
Antimicrobial peptidesAntimicrobial activityAnti-resistanceMultidrug-resistant bacteriaBiocompatibilityMultiple mechanisms  
New designed pH-responsive histidine-rich peptides with antitumor activity 期刊论文
JOURNAL OF DRUG TARGETING, 2021, 卷号: 29, 期号: 6, 页码: 651-659
Authors:  Chang, Linlin;  Bao, Hexin;  Yao, Jia;  Liu, H(刘晖);  Gou, SH(缑三虎);  Zhong, C(钟超);  Zhang, Y(张云);  Ni, JM(倪京满)
Favorite  |    Submit date:2021/04/16
Histidine-rich peptide  acid-activatable  antitumor  high efficiency  low toxicity  
Effect of N-methylated and fatty acid conjugation on analogs of antimicrobial peptide Anoplin 期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020, 卷号: 152
Authors:  Liu, Tianqi;  Zhu, Ningyi;  Zhong, C(钟超);  Zhu, Yuewen;  Gou, SH(缑三虎);  Chang, Linlin;  Bao, Hexin;  Liu, H(刘晖);  Zhang, Y(张云);  Ni, JM(倪京满)...Liu, Tianqi;  Zhu, Ningyi;  Zhong, C(钟超);  Zhu, Yuewen;  Gou, SH(缑三虎);  Chang, Linlin;  Bao, Hexin;  Liu, H(刘晖);  Zhang, Y(张云);  Ni, JM(倪京满)
Favorite  |    Submit date:2020/12/20
Antimicrobial peptides  Anoplin  N-methyl amino acid  Fatty acid conjugation  Proteolytic stability  
Design and synthesis of new N-terminal fatty acid modified-antimicrobial peptide analogues with potent in vitro biological activity 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182
Authors:  Zhong, Chao;  Liu, Tianqi;  Gou, SH(缑三虎);  He, Yongtao;  Zhu, Ningyi;  Zhu, Yuewen;  Wang, Li;  Liu, H(刘晖);  Zhang, Y(张云);  Yao, Jia...Zhong, Chao;  Liu, Tianqi;  Gou, SH(缑三虎);  He, Yongtao;  Zhu, Ningyi;  Zhu, Yuewen;  Wang, Li;  Liu, H(刘晖);  Zhang, Y(张云);  Yao, Jia;  Ni, JM(倪京满)
Favorite  |    Submit date:2020/08/27
Fatty acids conjugating  Dimerization  Anoplin  Hydrophobicity  Antimicrobial activity  
Amphiphilic Endomorphin-1 Derivative Functions as Self-assembling Nanomedicine for Effective Brain Delivery 期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2019, 卷号: 67, 期号: 0, 页码: 977-984
Authors:  Liu, H(刘晖);  Zhao, Xiaoning;  Liang, Shan;  Fan, LL(范临兰);  Li, Zhaojun;  Zhang, Y(张云);  Ni, JM(倪京满)
Favorite  |    Submit date:2019/10/10
peptide brain delivery  blood-brain barrier  endomorphin-1  self-assembling  disulfide bond  
Design of a new pH-activatable cell-penetrating peptide for drug delivery into tumor cells 期刊论文
Chemical Biology & Drug Design, 2019, 卷号: 94, 期号: 5, 页码: 1884-1893
Authors:  Zhang, Y(张云);  Li, Li;  Chang, Linlin;  Liu, H(刘晖);  Song, JJ(宋竟婧);  Liu, Yue;  Bao, Hexin;  Liu, Beijun;  Wang, R(王锐);  Ni, JM(倪京满)...Zhang, Y(张云);  Li, Li;  Chang, Linlin;  Liu, H(刘晖);  Song, JJ(宋竟婧);  Liu, Yue;  Bao, Hexin;  Liu, Beijun;  Wang, R(王锐);  Ni, JM(倪京满)
Favorite  |    Submit date:2020/08/20
acid-activated  anticancer drug delivery  cell-penetrating peptides  low cytotoxicity  pH-dependent antitumor activity  
Anti-atherosclerotic effect of Fermentum Rubrum and Gynostemma pentaphyllum mixture in high-fat emulsion- and vitamin D-3-induced atherosclerotic rats 期刊论文
Journal of the Chinese Medical Association, 2018, 卷号: 81, 期号: 5, 页码: 398-408
Authors:  Gou, San-Hu;  Liu, Bei-Jun;  Han, Xiu-Feng;  Wang, Li;  Zhong, Chao;  Liang, Shan;  Liu, H(刘晖);  Qiang, Y(强音);  Zhang, Y(张云);  Ni, JM(倪京满)...Gou, San-Hu;  Liu, Bei-Jun;  Han, Xiu-Feng;  Wang, Li;  Zhong, Chao;  Liang, Shan;  Liu, H(刘晖);  Qiang, Y(强音);  Zhang, Y(张云);  Ni, JM(倪京满)
Favorite  |    Submit date:2018/09/28
Atherosclerosis  Fermentum Rubrum  Gynostemma pentaphyllum  Gypenosides  Hyperlipidemia  Red yeast rice